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5-oxoprolinase (ATP-hydrolyzing)

catalyzes the hydrolysis of 5-oxo-L-proline to glutamate with concomitant stoichiometric cleavage of ATP to ADP & inorganic phosphate in the presence of Mg2+ & K+; EC number in first source
Also Known As:
5-OPase; 5-oxo-L-prolinase
Networked: 5 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Klimberg, V Suzanne: 1 article (01/2008)
2. Todorova, Valentina K: 1 article (01/2008)
3. Kaufmann, Yihong: 1 article (01/2008)
4. Luo, Shaoke: 1 article (01/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Drug Toxicity (Drug Safety)
3. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Melphalan (Alkeran)
2. 2-oxothiazolidine-4-carboxylic acid
3. Cysteine (L-Cysteine)
4. Glutathione (Reduced Glutathione)
5. Transferases
6. Messenger RNA (mRNA)
7. Ligases
8. Guanosine Triphosphate (GTP)
9. Glutaminase
10. gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)