|1.||Minagawa, K: 2 articles (08/2000 - 04/2000)|
|2.||Ninomiya, M: 2 articles (08/2000 - 04/2000)|
|3.||Kagawa, K: 2 articles (08/2000 - 04/2000)|
|4.||Kanemasa, T: 2 articles (08/2000 - 04/2000)|
|5.||Asakura, K: 2 articles (08/2000 - 04/2000)|
|6.||Nakajima, M: 1 article (08/2000)|
|7.||Yagami, T: 1 article (08/2000)|
|8.||Matsuo, Y: 1 article (04/2000)|
|9.||Kihara, T: 1 article (04/2000)|
|10.||Oshima, T: 1 article (04/2000)|
08/04/2000 - "In this study, we investigated the effect of alpha-eudesmol, which potently inhibits the presynaptic omega-agatoxin IVA-sensitive (P/Q-type) Ca(2+) channel, on neurogenic inflammation following electrical stimulation of rat trigeminal ganglion. "
08/04/2000 - "These results indicate that the anti-neurogenic inflammation action of alpha-eudesmol, which does not affect the cardiovascular system, may be due to its presynaptic inhibition of the neuropeptide release from perivascular trigeminal terminals. "
08/04/2000 - "We also suggest that the omega-agatoxin IVA-sensitive Ca(2+) channel blocker, alpha-eudesmol, may become useful for the treatment of the neurogenic inflammation in the trigemino-vascular system such as migraine."
|2.||Migraine Disorders (Migraine)
|3.||Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
04/07/2000 - "In the middle cerebral artery occlusion study, intracerebroventricular (i.c.v.) treatment with alpha-eudesmol significantly attenuated the post-ischemic increase in brain water content. "
04/07/2000 - "In the present study, we investigated the effects of alpha-eudesmol on brain edema formation and infarct size determined after 24 h of reperfusion following 1 h of middle cerebral artery occlusion in rats. "
|4.||Brain Edema (Cerebral Edema)
04/07/2000 - "Using a microdialysis technique, we further demonstrated that alpha-eudesmol inhibits the elevation of the extracellular concentration of glutamate during ischemia. "
04/07/2000 - "omega-agatoxin IVA-sensitive Ca(2+) channel blocker, alpha-eudesmol, protects against brain injury after focal ischemia in rats."
|2.||Glutamic Acid (Glutamate)