calpain Lp82

a lens-specific, calcium-activated isozyme from the calpain super family of cysteine proteases; Lp85 is an isoenzyme of Lp82; amino acid sequence in first source; GenBank AF091998

Also Known As:

Lp82, calpain; Lp85 calpain

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        Calpain: 2312
        calpain Lp82: 3
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        Calpain: 2312
        calpain Lp82: 3

Experts

1.	Kawabata, Yukiko: 1 article (07/2003)
2.	Sorimachi, Hiroyuki: 1 article (07/2003)
3.	Frueh, Beatrice: 1 article (04/2002)
4.	Hess, Otto M: 1 article (04/2002)
5.	Malina, Halina: 1 article (04/2002)
6.	Richter, Christoph: 1 article (04/2002)

Related Diseases

1.	Cataract (Cataracts) 11/01/1998 - "Lp82 calpain during rat lens maturation and cataract formation." 04/05/2002 - "Xanthurenic acid induces calpain Lp82 and caspases in the cells growing in the dark and can be involved in senile cataract development."
2.	Limb-girdle muscular dystrophy type 2A 07/01/2003 - "Among 14 human calpain genes, mutations in CAPN3, the gene for p94/calpain 3a and Lp82/calpain 3b, are the only example that genetically connects the calpain gene and human disease, in this case, limb-girdle muscular dystrophy type 2A (LGMD2A). "

Related Drugs and Biologics

1.	Caspases
2.	Calpain
3.	calpain p94
4.	xanthurenic acid