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octylmethoxycinnamate (octyl-methoxycinnamate)

a sunscreen used for prevention of DNA photodamage
Also Known As:
octyl-methoxycinnamate; octinoxate; 2-ethylhexyl-4-methoxycinnamate; 2-ethylhexyl-p-methoxycinnamate; Heliopan New; OMC cinnamate; Parsol MCX
Networked: 13 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Nash, J Frank: 1 article (04/2014)
2. Tanner, Paul R: 1 article (04/2014)
3. Maia Campos, Patricia M B G: 1 article (02/2013)
4. Tharmann, Julian: 1 article (02/2013)
5. Gaspar, Lorena R: 1 article (02/2013)
6. Liebsch, Manfred: 1 article (02/2013)
7. Kaygusuz, Arslan: 1 article (12/2009)
8. Aysan, Erhan: 1 article (12/2009)
9. Bektas, Hasan: 1 article (12/2009)
10. Pratt, Melanie D: 1 article (05/2009)

Related Diseases

1. Phototoxic Dermatitis (Phototoxicity)
2. Contact Dermatitis (Eczema, Contact)
12/01/2001 - "In this study in hairless mice, we compared two UVB absorbers, 2-ethylhexyl-p-methoxycinnamate (2-EHMC) and octyl-N-dimethyl-p-aminobenzoate (o-PABA), individually formulated in a common base lotion with a sunburn protection factor of 6. We measured their capacity to protect against suppression of the contact hypersensitivity (CHS) induced by three daily exposures of the dorsum to 6x the minimal erythemal/edematous dose (MED) of solar-simulated UV radiation (SSUV), in comparison with base lotion-treated mice exposed to 3 x 1 MED of SSUV. "
05/01/1992 - "This study compares the ability of two commonly used sunscreens--octyl dimethyl para-aminobenzoate (Padimate O) and 2-ethylhexyl-p-methoxycinnamate (2-EHMC)--to protect Langerhans cells (LC), Thy-1+ dendritic epidermal cells (Thy-1+ dEC), and local contact sensitivity (CS) from the effects of ultraviolet (UV) light. "
10/01/1995 - "We sought to determine whether the effect of preapplication of a sun protection factor (SPF) 29 sunscreen (containing octyl methoxycinnamate, oxybenzone, and octyl salicylate) could prevent local UVB-induced suppression of contact hypersensitivity to dinitrochlorobenzene (DNCB). "
12/01/1994 - "A series of experimental sunscreen preparations based on a common vehicle, containing increasing concentrations of either octyl-N-dimethyl-p-aminobenzoate (o-PABA) or 2-ethylhexyl-p-methoxycinnamate (2-EHMC) as the ultraviolet B (UVB) absorber, has been tested in the hairless mouse for the ability to protect from erythema, from the systemically suppressive effects of UVB (280-320 nm) radiation on contact hypersensitivity, and from photoisomerization of epidermal urocanic acid. "
05/01/2009 - "All had photocontact dermatitis or contact dermatitis to sunscreen chemicals, including benzophenone 3 (oxybenzone), butyl methoxydibenzoylmethane (avobenzone), and ethylhexyl methoxycinnamate (octinoxate). "
3. Sunburn
4. Photoallergic Dermatitis (Photoallergy)
5. Hypersensitivity (Allergy)

Related Drugs and Biologics

1. 4-tert-butyl-4'-methoxydibenzoylmethane (avobenzone)
2. Camphor
3. 4-Aminobenzoic Acid (4 Aminobenzoic Acid)
4. Sunscreening Agents (Sunscreens)
5. padimate-O
6. butyl-methoxydibenzoylmethane
7. octylmethoxycinnamate (octyl-methoxycinnamate)
8. oxybenzone (Solbar)
9. benzophenone
10. Urocanic Acid