HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

Ro 48-5695

derivative of bosentan

Also Known As:

Ro 485695; Ro-485695

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - Ro 48-5695: 3
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - Ro 48-5695: 3

Experts

1.	Hogaboam, C M: 1 article (03/2000)
2.	Huang, J Q: 1 article (03/2000)
3.	Hunt, R H: 1 article (03/2000)
4.	Padol, I: 1 article (03/2000)

Related Diseases

1.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/01/2000 - "The aim of this study was to establish the therapeutic effect of a 'new' endothelin receptor antagonist Ro 48-5695 in an animal model of inflammatory bowel disease. "
2.	Ulcer 04/01/1999 - "Bosentan and Ro 48-5695 possess weak antisecretory properties as tested in the mouse gastric gland assay, than cannot, alone, account for their anti-ulcer properties. "
3.	Proteinuria 04/01/1999 - "Ro 48-5695 had no effect on proteinuria. "
4.	Hypertension (High Blood Pressure) 04/01/1999 - "Ro 48-5695 attenuated the hypertension and the decline of creatinine clearance when treatment was started at 24 h, but not when started at 4 weeks. "
5.	Colitis 03/01/2000 - "Therapeutic effects of the endothelin receptor antagonist Ro 48-5695 in the TNBS/DNBS rat model of colitis."

Related Drugs and Biologics

1.	Endothelin Receptor Antagonists
2.	Therapeutic Uses
3.	Creatinine
4.	Bosentan (Tracleer)
5.	2,4-dinitrofluorobenzene sulfonic acid