LSG15 regimen

chemotherapy protocol consisting of above cpds (NITROSOUREA COMPOUNDS refers to ranimustine) for treatment of adult T cell leukemia

Networked: 5 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - LSG15 regimen: 5
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - LSG15 regimen: 5
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - LSG15 regimen: 5
Organic Chemicals: 133
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - Podophyllotoxin: 562
        Etoposide: 10706
        LSG15 regimen: 5
  - Naphthacenes
    - Anthracyclines: 9423
      - Daunorubicin: 2641
        Doxorubicin: 35390
        LSG15 regimen: 5
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnadienes
        Pregnadienetriols
        Prednisolone: 12013
        LSG15 regimen: 5
Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Anthracyclines: 9423
      - Daunorubicin: 2641
        Doxorubicin: 35390
        LSG15 regimen: 5
  - Glucosides: 639
    - Etoposide: 10706
      - LSG15 regimen: 5
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Secologanin Tryptamine Alkaloids: 81
      - Vinca Alkaloids: 463
        Vincristine: 9251
        LSG15 regimen: 5
        Vindesine: 836
        LSG15 regimen: 5
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        Vincristine: 9251
        LSG15 regimen: 5
        Vindesine: 836
        LSG15 regimen: 5
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        Vincristine: 9251
        LSG15 regimen: 5
        Vindesine: 836
        LSG15 regimen: 5

Experts

1.	Tobinai, Kensei: 2 articles (01/2012 - 12/2009)
2.	Chen, Chien-Kang: 1 article (10/2020)
3.	Hayashi, Seiichi: 1 article (10/2020)
4.	Ikari, Kenzo: 1 article (10/2020)
5.	Kusano, Junichi: 1 article (10/2020)
6.	Ogai, Asuka: 1 article (10/2020)
7.	Ozawa, Yuki: 1 article (10/2020)
8.	Yamamoto, Ryusei: 1 article (10/2020)
9.	Yoshida, Ranko: 1 article (10/2020)
10.	Arruda, Glória Bomfim: 1 article (01/2017)

Related Diseases

1.	Hepatomegaly 02/01/1999 - "He underwent a LSG15 regimen and hepatomegaly and lymphadenopathy improved markedly. "
2.	Lymphadenopathy 02/01/1999 - "He underwent a LSG15 regimen and hepatomegaly and lymphadenopathy improved markedly. "
3.	Lymphoma (Lymphomas) 01/01/2012 - "In case of acute, lymphoma, or unfavorable chronic subtypes (aggressive ATL), intensive chemotherapy like the LSG15 regimen (VCAP-AMP-VECP) is usually recommended if outside of clinical trials, based on the results of a phase 3 trial. " 01/01/2017 - "Complete response was achieved in seven smoldering patients with symptomatic treatment, in two with chronic disease using antivirals/chemotherapy, in one with acute disease using antivirals and in one lymphoma using the LSG15 regimen [vincristine, cyclophosphamide, doxorubicin, and prednisolone (VCAP); doxorubicin, ranimustine, and prednisolone (AMP); and vindesine, etoposide, carboplatin, and prednisolone (VECP)]. "
4.	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/01/2009 - "When there is no active trial or the patient is ineligible for a trial, we recommend intensive chemotherapy used for aggressive non-Hodgkin lymphoma such as the LSG15 regimen (VCAP-AMP-VECP) based on a recent phase III study. "
5.	Hand-Foot Syndrome 10/01/2020 - "[A Case of Adult T-Cell Leukemia/Lymphoma with Severe Hand-Foot Syndrome during Administration of Modified LSG15 Regimen]."

Related Drugs and Biologics

1.	Adenosine Monophosphate (AMP)
2.	Carboplatin (JM8)
3.	Vindesine (Vindesin)
4.	Vincristine (Oncovin)
5.	Prednisolone (Predate)
6.	Etoposide (VP 16)
7.	Doxorubicin (Adriamycin)
8.	Cyclophosphamide (Cytoxan)
9.	Antiviral Agents (Antivirals)
10.	ranimustine

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)