|1.||Monn, James A: 1 article (01/2005)|
|2.||Eberle, Elizabeth Lutz: 1 article (01/2005)|
|3.||Shannon, Harlan E: 1 article (01/2005)|
|4.||Peters, Stephen C: 1 article (01/2005)|
|5.||Jones, Carrie K: 1 article (01/2005)|
|6.||Webster, Amy A: 1 article (09/2002)|
|7.||Iyengar, Smriti: 1 article (09/2002)|
|8.||Kalra, Anshu B: 1 article (09/2002)|
|9.||Simmons, Rosa Maria A: 1 article (09/2002)|
|10.||Beart, P M: 1 article (07/2001)|
01/01/2005 - "Both LY379268 and LY389795 produced a dose-related reversal of carrageenan-induced thermal hyperalgesia and capsaicin-induced mechanical allodynia, but had no effect on carrageenan-induced mechanical allodynia. "
01/01/2005 - "In the present study, the effects of the selective group II metabotropic glutamate receptor agonists LY379268 and LY389795 were evaluated in the formalin test, carrageenan-induced thermal hyperalgesia and mechanical allodynia, and capsaicin-induced mechanical allodynia in rats. "
01/01/2005 - "Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing."
09/01/2002 - "LY354740, LY379268 and LY389795 attenuated late-phase paw-licking pain behavior in a dose-dependent manner in the formalin model of persistent pain. "
07/01/2001 - "Sound-induced clonic seizures in DBA/2 mice were transiently inhibited by both agonists intracerebroventricularly (i.c.v.), LY379268 ED(50)=0.08 [0.02-0.33]nmol and LY389795 ED(50)=0.82 [0.27-3.24]nmol or intraperitoneally (i.p.), LY379268 ED(50)=2.9 [0.9-9.6]mg/kg and LY389795 ED(50)=3.4 [1.0-11.7]mg/kg. Both mGlu(2/3) agonists inhibited seizures induced by the group I mGlu receptor agonist (R,S)-3,5-dihydroxyphenylglycine (DHPG), where LY379268, i.c.v. ED(50)=0.3 [0.02-5.0]pmol and LY389795, i.c.v. ED(50)=0.03 [0.05-0.19]nmol. "
|3.||Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)