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E 5842

Also Known As:

4-(4-fluorophenil)-1,2,3,4-tetrahydro-1-(4-(1,2,4-triazol-1-il)butyl)pyridine citrate; E-5842; E5842

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Triazoles: 1533
      - E 5842: 5
  - Pyridines: 88
    - E 5842: 5

Experts

1.	Fernández de Henestrosa, Antonio R: 4 articles (12/2008 - 12/2004)
2.	García, Concepción: 4 articles (12/2008 - 12/2004)
3.	Guzmán, Antonio: 4 articles (12/2008 - 12/2004)
4.	Marín, Ana-Paz: 4 articles (12/2008 - 12/2004)
5.	Tortajada, Araceli: 4 articles (12/2008 - 12/2004)
6.	Marcos, Ricard: 3 articles (12/2008 - 05/2008)
7.	Ruiz, María Teresa: 2 articles (12/2008 - 10/2008)
8.	Ruiz, Maria Teresa: 2 articles (05/2008 - 12/2004)
9.	Lloyd, Mel: 1 article (05/2008)
10.	Proudlock, Raymond J: 1 article (05/2008)

Related Diseases

1.	Hypothermia 12/01/2008 - "E-5842 administration produced marked hypothermia both in sigma(1)R-KO and WT mice. " 12/31/2004 - "Induction of micronuclei in mouse bone-marrow erythrocytes in association with hypothermia after administration of the sigma receptor ligand E-5842." 10/30/2008 - "Marked and long-lasting hypothermia was induced in male mice by oral administration of the antipsychotic compounds E-5842 (200 mg/kg) or chlorpromazine (100 mg/kg). " 05/31/2008 - "The produced mild hypothermia and absence of micronucleus induction was in contrast to the induction of MNPCE secondary to marked hypothermia reported for a structurally similar PTHPB-derived sigma-receptor ligand, the antipsychotic compound E-5842. "
2.	Psychotic Disorders (Schizoaffective Disorder) 06/01/2000 - "Esteve is developing E-5842, a sigma1 opioid receptor ligand, as a potential therapy for psychosis. "

Related Drugs and Biologics

1.	Ligands
2.	sigma Receptors (sigma Receptor)
3.	Antipsychotic Agents (Antipsychotics)
4.	Opioid Receptors (Opioid Receptor)
5.	Chlorpromazine (Thorazine)

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration