8-nitro-2'-deoxyguanosine

a marker of oxidation by reactive nitrogen intermediates in phagocytic neutrophils, generated through the cell-mediated myeloperoxidase pathway; structure in first source

Also Known As:

N-deoxyguanosine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Guanosine: 1156
        Deoxyguanosine: 166
        8-nitro-2'-deoxyguanosine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Guanosine: 1156
      - Deoxyguanosine: 166
        8-nitro-2'-deoxyguanosine: 2
  - Deoxyribonucleosides: 34
    - Deoxyguanosine: 166
      - 8-nitro-2'-deoxyguanosine: 2

Experts

1.	Bates, Andrew D: 1 article (11/2012)
2.	Bhamra, Inder: 1 article (11/2012)
3.	Compagnone-Post, Patricia: 1 article (11/2012)
4.	Cosstick, Richard: 1 article (11/2012)
5.	Iwanejko, Lesley A: 1 article (11/2012)
6.	O'Neil, Ian A: 1 article (11/2012)
7.	Geacintov, Nicholas E: 1 article (06/2005)
8.	Shafirovich, Vladimir: 1 article (06/2005)
9.	Shibutani, Shinya: 1 article (06/2005)
10.	Suzuki, Naomi: 1 article (06/2005)

Related Diseases

1.	Neoplasms (Cancer) 06/28/2005 - "8-Nitro-2'-deoxyguanosine (8-NO(2)-dG) DNA adducts are induced by the reactive nitrogen species and may be associated with the development of cancer in inflammatory tissues. "
2.	Inflammation (Inflammations) 11/01/2012 - "8-Nitro-2'-deoxyguanosine (8-nitrodG) is a relatively unstable, mutagenic lesion of DNA that is increasingly believed to be associated with tissue inflammation. "

Related Drugs and Biologics

1.	Reactive Nitrogen Species
2.	DNA Adducts
3.	DNA (Deoxyribonucleic Acid)