Substance P

An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.

Also Known As:

Euler-Gaddum Substance P; Hypothalamic Substance P; SP(1-11); Euler Gaddum Substance P; Substance P, Euler-Gaddum; Substance P, Hypothalamic

Pharmalogical Action Categories:

Neurotransmitter Agents

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Kinins: 2029
      - Tachykinins: 869
        Substance P: 4846
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Tachykinins: 869
        Substance P: 4846
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Kinins: 2029
      - Tachykinins: 869
        Substance P: 4846
  - Neuropeptides: 6772
    - Tachykinins: 869
      - Substance P: 4846
  - Oligopeptides: 519
    - Tachykinins: 869
      - Substance P: 4846
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Kinins: 2029
    - Tachykinins: 869
      - Substance P: 4846
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Kinins: 2029
      - Tachykinins: 869
        Substance P: 4846

NY 3640

Bio-Agent Context: Research Results