|1.||Sahin-Tóth, Miklós: 6 articles (07/2015 - 04/2006)|
|2.||Witt, Heiko: 3 articles (07/2015 - 01/2008)|
|3.||Hegyi, Eszter: 2 articles (07/2015 - 01/2014)|
|4.||Szabó, András: 2 articles (07/2015 - 11/2013)|
|5.||Bhaskar, Seema: 2 articles (12/2014 - 11/2013)|
|6.||Paliwal, Sumit: 2 articles (12/2014 - 11/2013)|
|7.||Zhou, Jiayi: 2 articles (11/2013 - 08/2011)|
|8.||Chandak, Giriraj Ratan: 2 articles (11/2013 - 11/2013)|
|9.||Chi, Cheng-Wu: 2 articles (07/2011 - 05/2011)|
|10.||Wang, Haibo: 2 articles (07/2011 - 05/2011)|
|1.||Cystic Fibrosis (Mucoviscidosis)
07/10/2015 - "Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis."
11/01/2013 - "Recently, chymotrypsin C (CTRC) variants that diminish its activity or secretion were found to predict susceptibility to chronic pancreatitis (CP). "
08/01/2011 - "Mutations in the chymotrypsin C (CTRC) gene encoding the digestive enzyme CTRC have been shown to increase the risk of chronic pancreatitis in European and Asian populations. "
08/01/2011 - "Chymotrypsin C mutations in chronic pancreatitis."
01/01/2009 - "Variations and haplotypes of the chymotrypsin C (CTRC) gene in Chinese patients with chronic pancreatitis (CP) and control subjects with genotype-phenotype correlation were investigated. "
03/01/2015 - "Herein, we describe the effect of the aberrant splicing of the c.273G>C (G91G) synonymous variation found in a 9-year-old white (ΔF508) patient affected by CF and pancreatitis associated with a variant in chymotrypsin C (CTRC). "
11/01/2013 - "Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk."
11/01/2013 - "Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants."
07/10/2015 - "Human chymotrypsin C (CTRC) protects against pancreatitis by degrading trypsinogen and thereby curtailing harmful intra-pancreatic trypsinogen activation. "
11/01/2013 - "The digestive enzyme chymotrypsin C (CTRC) protects against pancreatitis by promoting degradation of trypsinogen, thereby curtailing potentially harmful trypsinogen activation. "
|4.||Pancreatic Neoplasms (Pancreatic Cancer)
05/01/2011 - "We performed cell migration scratch assays and Transwell experiments, and found that cell migration ability was downregulated in pancreatic cancer Aspc-1 cells that overexpressed chymotrypsin C, whereas the cell migration ability was upregulated in Aspc-1 cells in which chymotrypsin C was suppressed. "
05/01/2011 - "The amount of chymotrypsin C in pancreatic cancer cells is only 20% of that found in normal cells. "
05/01/2011 - "Chymotrypsin C has been reported to be involved in cancer cell apoptosis, but its effect on pancreatic cancer cell migration is unclear. "
05/01/2011 - "We speculated that chymotrypsin C might regulate pancreatic cancer cell migration in relation to cytokeratin 18 expression."
05/01/2011 - "Effect of chymotrypsin C and related proteins on pancreatic cancer cell migration."
08/16/2013 - "Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop."
07/01/2011 - "Active chymotrypsin C was found to be different in the length of its 13-residue activation peptide due to carboxydipeptidase (present in the pancreas) degradation or autolysis of the activated chymotrypsin C itself, resulting in the removal of several C-terminus residues from the activation peptide. "
|1.||Serine Proteases (Serine Protease)
|2.||Carboxypeptidases A (Carboxypeptidase A)
|5.||Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)
|7.||Keratin-18 (Keratin 18)
|9.||Proteins (Proteins, Gene)
|10.||Lipoprotein Lipase (Diacylglycerol Lipase)