|1.||Yu, Yingjie: 1 article (03/2005)|
|2.||Xu, Hu: 1 article (03/2005)|
|3.||Sarkar, Fazlul H: 1 article (03/2005)|
|4.||Rishi, Arun K: 1 article (03/2005)|
|5.||Kucuk, Omer: 1 article (03/2005)|
|6.||Marciniak, Dorota: 1 article (03/2005)|
|7.||Majumdar, Adhip P N: 1 article (03/2005)|
|8.||Serini, Simona: 1 article (01/2005)|
|9.||Maggiano, Nicola: 1 article (01/2005)|
|10.||Calviello, Gabriella: 1 article (01/2005)|
|1.||Wounds and Injuries (Trauma)
03/20/2003 - "Indeed, immediately following a mechanical injury, heregulin-alpha activates erbB2 in cells at the edge of the wound, and this process hastens restoration of epithelial integrity. "
12/01/2002 - "HER-4 - another receptor for heregulin-alpha - is weakly present in occasional cells near the edge of the wound. "
09/01/2002 - "In this study, we examined the effects of EGF, TGFalpha, amphiregulin and heregulin-alpha (HRGalpha) on proliferation, wound closure, and the expression of their receptors c-erbB1-c-erbB4 in primary cultures of human urothelial cells in vitro. "
|2.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
|3.||Breast Neoplasms (Breast Cancer)
12/01/2002 - "Heregulin-alpha has already been shown to be the motility factor leading to migration of HER-2/neu-overexpressing breast cancer cells. "
04/19/2000 - "Binding of heregulin-alpha to the receptor complex on Paget cells results in the chemotaxis of these breast cancer cells, which eventually migrate into the overlying nipple epidermis."
03/01/2005 - "ERRP and trastuzumab, but not cetuximab, attenuated heregulin-alpha-induced activation of colon and breast cancer cells that expressed high levels of HER-2. "
05/22/1992 - "A 45-kilodalton protein heregulin-alpha (HRG-alpha) that specifically induced phosphorylation of p185erbB2 was purified from the conditioned medium of a human breast tumor cell line. "
07/15/2001 - "Treatment of MDA-MB-231 and MDA-MB-468 breast cancer cells with phosphoinositide-specific phospholipase-C abrogated the mitogenic response to two heparin-binding growth factors, heparin-binding epidermal growth factor-like growth factor and fibroblast growth factor 2. Stable transfection of these cells with a glypican-1 antisense construct markedly decreased glypican-1 protein levels and the mitogenic response to the same heparin-binding growth factors, as well as that to heregulin alpha, heregulin beta, and hepatocyte growth factor. "
|5.||Prostatic Neoplasms (Prostate Cancer)
02/01/1997 - "The overexpression of heregulin-alpha and erbB-3 in prostate cancer is detectable by immunostaining. "
02/01/1997 - "To examine the expression of heregulin-alpha (a new member of the epidermal growth factor family) and its receptor erbB-3 in human prostate cancer by immunohistochemistry, and to analyse their implication for clinical outcome. "
02/01/1997 - "Using specific anti-peptide antibodies, tumour samples from 50 consecutive patients with newly diagnosed prostate cancer (18 well, 15 moderately and 17 poorly differentiated) and four patients with benign prostatic hyperplasia (BPH) were immunostained for heregulin-alpha (an isoform of heregulin) and erbB-3 proteins. "
|1.||Epidermal Growth Factor (EGF)
|2.||Transforming Growth Factor alpha (TGF-alpha)
|3.||amphiregulin (schwannoma-derived growth factor)
|4.||Neuregulin-1 (Neuregulin 1)
|6.||Intercellular Signaling Peptides and Proteins (Growth Factors)
|7.||erbB-3 Receptor (Receptor, erbB 3)
|8.||beta Carotene (Betacarotene)
|9.||Hepatocyte Growth Factor (Growth Factor, Hepatocyte)
|10.||Conditioned Culture Media