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2-benzyl-3-iodo-propanoic acid

Also Known As:

BIPA

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        2-benzyl-3-iodo-propanoic acid: 12
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - 2-benzyl-3-iodo-propanoic acid: 12
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - 2-benzyl-3-iodo-propanoic acid: 12

Experts

1.	Lopez, Job E: 2 articles (01/2022 - 01/2013)
2.	Curtis, Michael W: 1 article (01/2022)
3.	Embers, Monica E: 1 article (01/2022)
4.	Gettings, Jenna R: 1 article (01/2022)
5.	Kneubehl, Alexander R: 1 article (01/2022)
6.	Krishnavajhala, Aparna: 1 article (01/2022)
7.	Yabsley, Michael J: 1 article (01/2022)
8.	Banerjee, Srijon K: 1 article (01/2021)
9.	Crane, Samantha D: 1 article (01/2021)
10.	Eichelberger, Kara R: 1 article (01/2021)

Related Diseases

1.	Infections 01/01/2016 - "In a mouse intranasal infection model, the BipA mutant showed significantly lower levels of initial lung colonization than did the parental strain (P < 0.01), suggesting that BipA might be a critical virulence factor in B. " 01/01/2013 - "Moreover, mice continued to generate an antibody response against BipA one year after the initial infection, further demonstrating the protein's potential toward identifying endemic foci for B. " 01/01/2013 - "These studies indicated that BipA is antigenic in both animal systems after infection by tick bite, yet serum antibodies failed to bind to B. " 08/21/2015 - "BipA-dependent expression of virulence factors occurs under starvation conditions, such as encountered during infection of a host. "
2.	Relapsing Fever 01/01/2013 - "Thus far, BipA appears unique to relapsing fever spirochetes. " 01/01/2013 - "These initial studies support the hypothesis that BipA is a spirochete antigen unique to a relapsing fever Borrelia species, and could be used to improve efforts for identifying B. " 01/01/2022 - "Characterization of Immunological Responses to Borrelia Immunogenic Protein A (BipA), a Species-Specific Antigen for North American Tick-Borne Relapsing Fever." 01/01/2013 - "The antigen remains unidentified outside of these pathogens, while interspecies amino acid identity for BipA in relapsing fever spirochetes is only 24-36%. "
3.	Tick Bites 01/01/2013 - "These studies indicated that BipA is antigenic in both animal systems after infection by tick bite, yet serum antibodies failed to bind to B. "
4.	Starvation 08/21/2015 - "BipA-dependent expression of virulence factors occurs under starvation conditions, such as encountered during infection of a host. " 01/01/2006 - "In combination with real-time reverse transcription polymerase chain reaction (RT-PCR), we have used it to analyse the expression pattern of the genes encoding the RNA polymerase subunits (the core enzyme and the 24 sigma factors), and various proteins involved in global regulation (Crc, Lrp, Fur, Anr, Fis, CsrA, IHF, HupA, HupB, HupN, BipA and several MvaT-like proteins), during the shift from exponential growth in rich medium into starvation and stress brought about by the entry into stationary phase. " 08/01/2011 - "The combination of genomic and proteomic approaches illustrated that altered expression or mutations in critical genes, such as those encoding a Ser/Thr kinase, carbon-starvation protein CstA, glutamine synthetase, GTP-binding protein BipA, ribonucleotide-diphosphate reductase and phosphate transporter, and alterations in the translational profile of lipoproteins or outer membrane proteins are likely to account for the virulence attenuation in strain IPAV."
5.	Whooping Cough (Pertussis) 02/01/2005 - "pertussis expresses in vitro the Bvg(i) phase at the human nasal temperature, anti-BipA antibodies were undetectable in a large collection of sera from pertussis patients." 02/01/2005 - "pertussis displays in its Bvg(i) phase a characteristic colony morphology and hemolytic activity and expresses a Bvg(i)-phase-specific polypeptide called BipA, whose synthesis is regulated by bvgAS at the transcriptional level. " 08/01/2014 - "Finally, we confirmed that bipA is expressed during respiratory tract infection of mice, and that anti-BipA antibodies are present in the serum of convalescent whooping cough patients. " 08/01/2014 - "Together, these data suggest that biofilm proteins and in particular BipA may be of interest for inclusion into future pertussis vaccines. "

Related Drugs and Biologics

1.	Antibodies
2.	Antigens
3.	Proteins (Proteins, Gene)
4.	Virulence Factors (Pathogenicity Factors)
5.	Phosphate Transport Proteins (Phosphate Transporter)
6.	GTP Phosphohydrolases (GTPases)
7.	GTP-Binding Proteins (G-Protein)
8.	Protein S
9.	Vaccines
10.	Staphylococcal Protein A (Protein A)