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yomogin

eudesmane sesquiterpene from Artemisia princeps; inhibits inducible nitric oxide synthase production in macrophages; structure in first source

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Polycyclic Sesquiterpenes: 9
        Eudesmane Sesquiterpenes: 2
        yomogin: 4
Polycyclic Compounds: 6
- Polycyclic Sesquiterpenes: 9
  - Eudesmane Sesquiterpenes: 2
    - yomogin: 4

Experts

1.	Ha, Joo-Hun: 1 article (07/2004)
2.	Jeong, Seoung-Hee: 1 article (07/2004)
3.	Koo, Sung-Ja: 1 article (07/2004)
4.	Lee, Kyung-Tae: 1 article (07/2004)
5.	Park, Hee-Juhn: 1 article (07/2004)
6.	Ryu, Shi-Yong: 1 article (07/2004)
7.	Kim, Seung Hyun: 1 article (10/2002)
8.	Kim, Tae Sung: 1 article (10/2002)

Related Diseases

1.	Leukemia 07/01/2004 - "In this study, we investigated the effects of yomogin on the cytotoxicity, induction of apoptosis, and putative pathways of its actions in human promyelocytic leukemia cells. " 10/01/2002 - "In this study, the effect of yomogin, a eudesmane sesquiterpene lactone isolated from Artemisia princeps with anti-inflammatory activity, was investigated in human promyelocytic leukemia HL-60 cells. " 10/01/2002 - "Synergistic induction of 1,25-dihydroxyvitamin D(3)- and all-trans-retinoic acid-induced differentiation of HL-60 leukemia cells by yomogin, a sesquiterpene lactone from Artemisia princeps."
2.	Inflammation (Inflammations) 12/31/2022 - "Collectively, these results suggest that yomogin suppresses neuroinflammation by regulating the MAPK pathway and it could be a potential candidate for inflammation-mediated neurological diseases." 08/01/1998 - "Thus, yomogin may be a useful candidate for the development of new drugs to treat endotoxemia and inflammation accompanied by the overproduction of NO."
3.	Endotoxemia 08/01/1998 - "Thus, yomogin may be a useful candidate for the development of new drugs to treat endotoxemia and inflammation accompanied by the overproduction of NO."
4.	Neoplasms (Cancer) 07/01/2004 - "Yomogin is an active compound isolated from Artemisia princep, a traditional Oriental medicinal herb, which has been shown to inhibit tumor cell proliferation. "
5.	Myeloid Leukemia (Leukemia, Myelocytic) 10/01/2002 - "These results suggest that yomogin may be useful in combination with 1,25-(OH)(2) D(3) or all- trans-RA in the differentiation therapy for myeloid leukemias. "

Related Drugs and Biologics

1.	Sesquiterpenes
2.	Lactones
3.	eudesmane
4.	Tretinoin (Retinoic Acid)
5.	Lipopolysaccharides

Related Therapies and Procedures

1.	Therapeutics