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pancreatic elastase II

human pancreatic elastase is type II

Also Known As:

elastase 2; elastase II

Networked: 13 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        pancreatic elastase II: 13
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        pancreatic elastase II: 13

Experts

1.	Bonnart, Chrystelle: 2 articles (08/2010 - 03/2010)
2.	Deraison, Céline: 2 articles (08/2010 - 03/2010)
3.	Hovnanian, Alain: 2 articles (08/2010 - 03/2010)
4.	Lacroix, Matthieu: 2 articles (08/2010 - 03/2010)
5.	Cepinskas, Gediminas: 1 article (06/2020)
6.	Daley, Mark: 1 article (06/2020)
7.	Dos Santos, Claudia C: 1 article (06/2020)
8.	Fraser, Douglas D: 1 article (06/2020)
9.	Gill, Sean E: 1 article (06/2020)
10.	Martin, Claudio: 1 article (06/2020)

Related Diseases

1.	Chronic Obstructive Pulmonary Disease (COPD) 09/01/2012 - "Cases with prevalent COPD (n=145), incident NSCLC (n=203) or prevalent COPD plus NSCLC (n=118) were compared to disease-free controls (n=317), to assess two functional polymorphisms in serpin peptidase inhibitor, clade A, member 1 (SERPINA1), which encodes AAT, and eleven tagging polymorphisms in and around elastase 2 (ELA2), which encodes NE. "
2.	Netherton Syndrome 08/01/2010 - "[Elastase 2, a key player in the integrity of the epidermal barrier and in Netherton syndrome]." 03/01/2010 - "Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing."
3.	Pancreatitis 02/01/1978 - "Substantial amounts of alpha2-macroglobulin-bound trypsin and elastase 2, entering the circulation from the peritoneal cavity, might be responsible for certain serious complications seen in acute pancreatitis. " 03/01/1982 - "6. We propose that an elastase-like enzyme, probably different from elastase 1 or elastase 2, is liberated from the pancreas into blood during acute pancreatitis and becomes combined with alpha 2-macroglobulin." 02/01/1978 - "Total protein, alpha1-antitrypsin, alpha2-macroglobulin, amylase, methemalbumin, tryptic amidase activity, radioimmunoassayable elastase 2, and three lysosomal hydrolases were determined in the ascites fluid from patients with acute pancreatitis. "
4.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 02/22/2010 - "Expression levels of the cell surface glycoprotein, CD7, and the serine protease, elastase 2 (ELA2), in the leukemic cells of patients with chronic myeloid leukemia (CML) have been associated with clinical outcome. "
5.	Wiskott-Aldrich Syndrome 03/01/2009 - "Patients with autosomal dominant (AD), sporadic and X-linked severe congenital neutropenia (SCN) may have mutations in the elastase 2 (ELA2) or Wiskott-Aldrich syndrome (WAS) genes. "

Related Drugs and Biologics

1.	Serpins
2.	Protease Inhibitors (Protease Inhibitor)
3.	Proteins (Proteins, Gene)
4.	Pregnancy-Associated alpha 2-Macroglobulins (alpha 2 Macroglobulin)
5.	Interleukin-18 (Interleukin 18)
6.	Interferon-gamma (Interferon, gamma)
7.	Serine Proteases (Serine Protease)
8.	Cathepsin G
9.	Chemokine CXCL10
10.	Granzymes (Granzyme)