theasaponin E1

acylated oleanene-type triterpene oligoglycoside from the seeds of the tea plant Camellia sinensis; structure in first source

Also Known As:

21-O-angeloyl-22-O-acetyltheasapogenol E 3-O-(beta-D-galactopyranosyl(1-->2))(beta-D-xylopyranosyl(1-->2)-alpha-L - arabinopyranosyl (1-->3))-beta-D-glucopyranosiduronic acid; theasaponin E(1)

Networked: 5 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Khan, Muhammad Imran: 3 articles (03/2022 - 05/2020)
2.	Kim, Jong Deog: 3 articles (03/2022 - 05/2020)
3.	Shin, Jin Hyuk: 3 articles (03/2022 - 05/2020)
4.	Khan, Muhammad Zubair: 2 articles (03/2022 - 01/2021)
5.	Kim, Min Yong: 2 articles (03/2022 - 05/2020)
6.	Lee, Young Bok: 2 articles (03/2022 - 01/2021)
7.	Shin, Tai Sun: 2 articles (03/2022 - 05/2020)
8.	Chen, Yi Charlie: 1 article (03/2021)
9.	Li, Bo: 1 article (03/2021)
10.	Rankin, Gary O: 1 article (03/2021)

Related Diseases

1.	Obesity 01/01/2021 - "We evaluated the synergistic antiangiogenesis, antiadipogenic and antilipogenic efficacy of standardized rebaudioside A, sativoside, and theasaponin E1 formulations (RASE1) in vitro in human umbilical vein endothelial cells (HUVECs), 3T3-L1 preadipocytes respectively, and in vivo using a high-fat and carbohydrate diet-induced obesity mouse model. "
2.	Neuroblastoma 05/16/2020 - "The effect of theasaponin E1 on these crucial enzymes was investigated by RT-PCR, ELISA, western blotting and fluorometric assays using mouse neuroblastoma cells (SweAPP N2a). " 03/24/2022 - "In the present study, we isolated theasaponin E1 from ethanol extract of green tea seed and evaluated its therapeutic inhibitory effects on tau hyper-phosphorylation and neuroinflammation in neuroblastoma (SHY-5Y) and glioblastoma (HTB2) cells, respectively, to elucidate the mechanism of the inhibitory effects. "
3.	Glioblastoma (Glioblastoma Multiforme) 03/24/2022 - "In the present study, we isolated theasaponin E1 from ethanol extract of green tea seed and evaluated its therapeutic inhibitory effects on tau hyper-phosphorylation and neuroinflammation in neuroblastoma (SHY-5Y) and glioblastoma (HTB2) cells, respectively, to elucidate the mechanism of the inhibitory effects. "
4.	Neuroinflammatory Diseases 03/24/2022 - "In the present study, we isolated theasaponin E1 from ethanol extract of green tea seed and evaluated its therapeutic inhibitory effects on tau hyper-phosphorylation and neuroinflammation in neuroblastoma (SHY-5Y) and glioblastoma (HTB2) cells, respectively, to elucidate the mechanism of the inhibitory effects. "
5.	Ovarian Neoplasms (Ovarian Cancer) 03/17/2021 - "Theasaponin E1 Inhibits Platinum-Resistant Ovarian Cancer Cells through Activating Apoptosis and Suppressing Angiogenesis."

Related Drugs and Biologics

1.	Carbohydrates
2.	rebaudioside A
3.	Tea
4.	Ethanol (Ethyl Alcohol)
5.	NF-kappa B (NF-kB)
6.	Cytokines
7.	Interleukin-6 (Interleukin 6)
8.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9.	Platinum
10.	Enzymes

Related Therapies and Procedures

1.	Chemoprevention