|1.||Wong, David T W: 1 article (01/2004)|
|2.||Hinds, Philip: 1 article (01/2004)|
|3.||Hu, Guo-Fu: 1 article (01/2004)|
|4.||Tsuji, Takanori: 1 article (01/2004)|
|5.||Kim, Yong: 1 article (01/2004)|
|6.||Hu, Miaofen G: 1 article (01/2004)|
|7.||McBride, Jim: 1 article (01/2004)|
|8.||Dai, J C: 1 article (08/2001)|
|9.||Hunzicker, A: 1 article (08/2001)|
|10.||Flohr, C: 1 article (08/2001)|
01/01/1989 - "DNA Polymerase-alpha/primase complexes have been isolated from human neuroblastoma IMR-32, embryonic chicken brains (ECB) and rat prostate tumor PA-3 cells. "
11/01/1992 - "fasciculata RP-A substitutes for human RP-A in the large tumor antigen-dependent unwinding of the SV40 origin of replication and stimulates both DNA synthesis and DNA priming by human DNA polymerase alpha/primase, but it does not support efficient SV40 DNA replication in vitro. "
10/21/1994 - "Human DNA libraries were screened for DNA synthesis activity in vitro using purified DNA polymerase alpha/primase and a viral DNA helicase (simian virus 40 large tumor antigen). "
09/01/1991 - "The addition of DNA polymerase alpha-primase purified from mouse cells induced the replication of polyomavirus DNA in a cell-free system containing polyomavirus large tumor antigen and nonpermissive cell extracts, such as human and insect cell extracts. "
12/01/1998 - "Physical interactions of simian virus 40 (SV40) large tumor (T) antigen with cellular DNA polymerase alpha-primase (Pol/Prim) and replication protein A (RPA) appear to be responsible for multiple functional interactions among these proteins that are required for initiation of viral DNA replication at the origin, as well as during lagging-strand synthesis. "
11/01/1993 - "We propose that a novel 12S DNA polymerase alpha-primase complex prone to disruption by salt is induced by MVM infection and that the DNA primase component of the complex is modified."
05/30/1989 - "The ratio of primase-free DNA polymerase alpha to the DNA polymerase alpha-primase complex increased from 1.5 to greater than 100 during the course of infection, and free primase was produced during the MVM replicative cycle."
|5.||Experimental Liver Neoplasms
08/01/2001 - "Thus, the amino acid change found in subunit B appears to result in a conformational change of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells. "
08/01/2001 - "A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex."
08/01/2001 - "To prove or disprove this hypothesis, we looked for mutations in the cDNA sequences of the four subunits of DNA polymerase alpha-primase from both highly malignant Novikoff hepatoma cells and regenerating normal rat liver and compared physicochemical and catalytic properties of the DNA polymerase alpha-primase complexes purified from both sources. "
|1.||DNA (Deoxyribonucleic Acid)
|3.||Proteins (Proteins, Gene)
|4.||Replication Protein A
|5.||DNA Primase (Primase)
|7.||Replication Protein C (Replication Factor C)
|8.||Cyclin-Dependent Kinase 2
|9.||A-Form DNA (A-DNA)