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SU 5416 (SU5416)

SU5416, a synthetic compound, is a potent and selective inhibitor of the Flk-1/KDR receptor tyrosine kinase that is presently under evaluation in phase I trial studies for the treatment of human cancers
Also Known As:
SU5416; Semaxinib; 3-(2,4-dimethylpyrrol-5-yl)methylidene-indolin-2-one; SU-5416
Networked: 184 relevant articles (24 outcomes, 51 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Voelkel, Norbert F: 14 articles (02/2015 - 04/2002)
2. Scigalla, Paul: 7 articles (07/2006 - 03/2002)
3. Tuder, Rubin M: 6 articles (09/2015 - 04/2002)
4. Kraskauskas, Donatas: 6 articles (02/2015 - 09/2010)
5. Farkas, Laszlo: 6 articles (02/2015 - 10/2012)
6. Lipson, Kenneth E: 6 articles (04/2008 - 03/2003)
7. Mizuno, Shiro: 5 articles (02/2015 - 09/2010)
8. Gomez-Arroyo, Jose: 5 articles (02/2015 - 11/2012)
9. Bogaard, Harm J: 4 articles (02/2015 - 09/2010)
10. Oka, Masahiko: 4 articles (11/2014 - 06/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Anoxia (Hypoxia)
3. Ovarian Neoplasms (Ovarian Cancer)
4. Neuroblastoma
5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
3. Protein-Tyrosine Kinases (Tyrosine Kinase)
4. SU 6668 (SU6668)
5. Paclitaxel (Taxol)
6. Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)
7. Phosphotransferases (Kinase)
8. Angiogenesis Inhibitors
9. glucuronyl glucosamine glycan sulfate (Vessel)
10. tyrosine receptor (receptor, tyrosine)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)
3. Radiotherapy
4. Pneumonectomy (Lung Volume Reduction)
5. Subcutaneous Injections