T 30695 (T30695)

an oligonucleotide composed of only deoxyguanosine and thymidine; contains single phosphorothioate internucleoside linkages at its 5' and 3' ends; structure first source

Also Known As:

T30695; T-30695

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - T 30695: 1

Related Diseases

Infections

10/14/1997 - "Comparing structural stability with the capacity of the folded oligomers to inhibit the HIV-1 integrase enzyme in vitro or HIV-1 infection in cell culture, we have found that the folding and activity data are highly correlated, suggesting that formation of an orderly, ion-coordinated loop structure similar to that in T30177 or T30695 may be a prerequisite for both integrase inhibition and anti-HIV-1 activity."

Related Drugs and Biologics

1.	Integrases
2.	Enzymes
3.	Human immunodeficiency virus 1 p31 integrase protein
4.	T 30177 (AR 177)