|1.||Capecchi, Mario R: 4 articles (11/2013 - 04/2007)|
|2.||Eid, Josiane E: 4 articles (11/2013 - 10/2007)|
|3.||Garcia, Christina B: 4 articles (11/2013 - 10/2007)|
|4.||Saito, Tsuyoshi: 4 articles (01/2013 - 05/2004)|
|5.||Ladanyi, Marc: 4 articles (07/2006 - 01/2002)|
|6.||Larsson, Olle: 4 articles (04/2003 - 01/2002)|
|7.||Toguchida, Junya: 3 articles (07/2009 - 05/2006)|
|8.||Wang, Jian: 3 articles (06/2009 - 07/2002)|
|9.||Haldar, Malay: 3 articles (04/2009 - 04/2007)|
|10.||Iwamoto, Yukihide: 3 articles (02/2008 - 05/2004)|
|1.||Synovial Sarcoma (Synovioma)
01/01/2009 - "This study demonstrates deregulation of polycomb activity by the synovial sarcoma-associated SYT-SSX2 oncogene, also known as SS18-SSX2. "
06/01/2004 - "We reviewed previous reports of thoracic synovial sarcomas containing an analysis of the SYT-SSX fusion transcript and found that case 2 in the present study was the first description of a biphasic synovial sarcoma of the thorax with an SYT-SSX2 fusion transcript. "
06/01/2004 - "Previous studies have shown that SYT-SSX1 is the most common SYT-SSX fusion transcript in biphasic synovial sarcomas of the limbs. "
01/01/2013 - "The SYT-SSX fusion protein and histological epithelial differentiation in synovial sarcoma: relationship with extracellular matrix remodeling."
08/01/2012 - "Synovial sarcoma of the tongue confirmed by molecular detection of the SYT-SSX2 fusion gene transcript."
02/01/2010 - "Patients with the SYT-SSX1 fusion gene have a worse clinical outcome than patients with SYT-SSX2-positive tumors. "
06/01/2009 - "SYT-SSX1 (risk ratio [RR] = 2.032, P = 0.004), larger tumor size (RR = 1.859, P = 0.008), and aggressive Fédération Nationale des Centers de Lutte Contre le Cancer grade (RR = 2.094, P = 0.001) were adverse predictors for disease-specific survival. "
04/15/2009 - "CreER-based sporadic expression both avoids the severe early developmental phenotypes associated with widespread SYT-SSX2 expression and better models natural pathogenesis of cancers in which transformed cells usually arise within an environment of largely normal cells. "
02/01/2006 - "The finding of the SYT-SSX2 translocation is generally associated with a better prognosis, besides tumor negative margins after excision offer the possibility of a better outlook for this patient."
03/01/2005 - "Both neoplasms contained the SYT-SSX1 type of the diagnostic translocation t(X;18) as detected by the reverse-transcription polymerase chain reaction analysis. "
|3.||Genetic Translocation (Chromosomal Translocation)
03/01/2014 - "The diagnosis was confirmed in molecular biology by reverse transcription polymerase chain reaction (RT-PCR) which demonstrated a unique chromosomal translocation t(X;18) with SYT-SSX2 fusion transcripts. "
05/01/2004 - "Synovial sarcomas (SS) consistently show a characteristic chromosomal translocation, t(X;18)(p11;q11), which usually leads to the formation of 2 chimeric fusion transcripts, SYT-SSX1 and -SSX2. "
06/01/2000 - "Synovial sarcomas (SS) are characterized by a chromosomal translocation t(X;18)(p11.2;q11.2) which usually fuses the SYT gene from chromosome 18 to SSX1 or SSX2 genes on chromosome X. Also, a variant SYT-SSX4 fusion gene has recently been shown in a single SS case. "
06/22/2006 - "SYT-SSX2 is the fusion product of the chromosomal translocation, t(X;18)(p11.2;q11.2), which occurs in synovial sarcoma, a soft tissue tumor. "
02/16/2006 - "Synovial sarcoma is an aggressive soft tissue tumor characterized by a specific chromosomal translocation between chromosome 18 and X. This translocation can generate a fusion transcript encoding SYT-SSX1, a transforming oncoprotein. "
|4.||Neoplasm Metastasis (Metastasis)
06/01/2009 - "Moreover, SYT-SSX1 was an adverse predictor for disease-specific survival and metastasis-free survival, but had no relation to local recurrence-free survival. "
11/16/2001 - "SYT-SSX1 fusion transcript appeared to be an independent, though not reaching statistical significance (P = 0.183), prognostic factor clearly associated with a reduced metastasis-free survival. "
04/01/2000 - "The hazard ratio for metastasis associated with the SYT-SSX1 fusion transcripts was 7 (95% CI 1.5-36, log-rank p = 0.004). "
06/01/2009 - "Besides, SYT-SSX1 (RR = 1.859, P = 0.037), older age (RR = 1.799, P = 0.040), and aggressive International Union Against Cancer stage (RR = 3.690, P < 0.001) proved to be adverse prognostic factors for metastasis-free survival. "
03/01/2005 - "Late solitary bone metastasis of a primary pulmonary synovial sarcoma with SYT-SSX1 translocation type: case report with a long follow-up."
|5.||Sarcoma (Soft Tissue Sarcoma)
05/03/2012 - "These results support the notion that the SYT-SSX2 nuclear function and differentiation effects are conserved throughout sarcoma development and are required for its maintenance beyond the initial phase. "
10/01/2005 - "We report, to our knowledge, the first epithelioid sarcoma in which the presence of SYT-SSX1 fusion gene has been detected by means of conventional RT-PCR analysis and sequencing, real-time RT-PCR and FISH. "
10/01/2005 - "Epithelioid sarcoma with SYT-SSX1 fusion gene expression: molecular and cytogenetic analysis."
04/01/2012 - "Primary Monophasic Synovial Sarcoma Arising in the Mesentery: Case Report of an Extremely Rare Mesenteric Sarcoma Confirmed by Molecular Detection of a SYT-SSX2 Fusion Transcript."
01/01/1998 - "One case of recurrent spindle cell sarcoma originally classified as a fibrosarcoma revealed a SYT-SSX2 fusion transcript. "
|1.||SYT-SSX fusion protein
|2.||RNA-Directed DNA Polymerase (Reverse Transcriptase)
|5.||Proteins (Proteins, Gene)
|6.||RNA (Ribonucleic Acid)
|10.||Oncogene Proteins (Oncogene Protein)