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sulfo-Lewis(a)

sulfo Lewis blood group system

Also Known As:

3-sulfo-Lewis(a); HSo3-3Gal beta1-3(Fuc alpha1-4)GlcNAc; sulfo-Le(a); sulfo-Lewis alpha

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Blood Group Antigens: 5213
      - Lewis Blood Group Antigens: 208
        sulfo-Lewis(a): 4
  - Isoantigens: 1221
    - Blood Group Antigens: 5213
      - Lewis Blood Group Antigens: 208
        sulfo-Lewis(a): 4
Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - sulfo-Lewis(a): 4

Experts

1.	Burgdorf, Sven: 1 article (04/2011)
2.	Kalay, Hakan: 1 article (04/2011)
3.	Kurts, Christian: 1 article (04/2011)
4.	Litjens, Manja: 1 article (04/2011)
5.	Saeland, Eirikur: 1 article (04/2011)
6.	Singh, Satwinder Kaur: 1 article (04/2011)
7.	Streng-Ouwehand, Ingeborg: 1 article (04/2011)
8.	Unger, Wendy W: 1 article (04/2011)
9.	van Kooyk, Yvette: 1 article (04/2011)
10.	Bodger, K: 1 article (09/2003)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2003 - "Sulfomucin staining in dysplasia and cancer was variable, but HID positive areas were always sulfo-Lewis(a) positive. " 04/01/2011 - "We conclude that modification of antigen with either 3-sulfo-Lewis(A) or tri-GlcNAc enhances cross-presentation and permits Th1 skewing, through specific targeting of the MR, which may be beneficial for DC-based vaccination strategies to treat cancer." 03/07/1995 - "Selectin ligands and tumor-associated carbohydrate structures: specificities of alpha 2,3-sialyltransferases in the assembly of 3'-sialyl-6-sialyl/sulfo Lewis a and x, 3'-sialyl-6'-sulfo Lewis x, and 3'-sialyl-6-sialyl/sulfo blood group T-hapten."
2.	Adenocarcinoma 01/01/2000 - "In Barrett's epithelium with adenocarcinoma, all Barrett's epithelium adjacent to carcinomas showed a predominance of immunoreactivity to sulfo-Lewis(a). " 09/01/2003 - "Sections containing gastric IM or BO (some associated with dysplasia or adenocarcinoma) were stained by the HID/alcian blue (AB) method and immunohistochemically (antibody 91.9H) to detect sulfo-Lewis(a). "
3.	Metaplasia 09/01/2003 - "Detection of sulfated glycoproteins in intestinal metaplasia: a comparison of traditional mucin staining with immunohistochemistry for the sulfo-Lewis(a) carbohydrate epitope."
4.	Carcinoma (Carcinomatosis) 01/01/2000 - "In Barrett's epithelium with adenocarcinoma, all Barrett's epithelium adjacent to carcinomas showed a predominance of immunoreactivity to sulfo-Lewis(a). "

Related Drugs and Biologics

1.	Antigens
2.	N,N',N''-triacetylchitotriose
3.	Carbohydrates
4.	Selectins
5.	Mucins
6.	Ligands
7.	Haptens
8.	Glycoproteins (Glycoprotein)
9.	Blood Group Antigens (Blood Groups)
10.	Epitopes