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indium 111-cT84.66 monoclonal antibody

used in treating presurgical colorectal cancer patients

Also Known As:

111In-Z2D3; 111In-cT84.66; 111In-chimeric T84.66 monoclonal antibody

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Neoplasms (Cancer) 12/01/1998 - "Although clinically important changes in biodistribution, pharmacokinetics and tumor targeting with increasing protein doses of 111In-cT84.66 were not demonstrated, the results do suggest that antibody clearance from the blood is driven by hepatic uptake and metabolism, with more rapid blood clearance seen in patients with liver metastases. "
2.	Neoplasm Metastasis (Metastasis) 12/01/1998 - "Although clinically important changes in biodistribution, pharmacokinetics and tumor targeting with increasing protein doses of 111In-cT84.66 were not demonstrated, the results do suggest that antibody clearance from the blood is driven by hepatic uptake and metabolism, with more rapid blood clearance seen in patients with liver metastases. "

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