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arsenite methyltransferase

converts arsenite to monomethylarsonic acid (MMA); MW 46 kDa

Also Known As:

liver arsenite methyltransferase

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - One-Carbon Group Transferases
      - Methyltransferases: 5778
        arsenite methyltransferase: 6

Experts

1.	Cebrián, Mariano E: 1 article (01/2022)
2.	Gamboa-Loira, Brenda: 1 article (01/2022)
3.	López-Carrillo, Lizbeth: 1 article (01/2022)
4.	Rangel-Moreno, Karla: 1 article (01/2022)
5.	He, Yuefeng: 1 article (02/2021)
6.	Sun, Mingjun: 1 article (02/2021)
7.	Tan, Jingwen: 1 article (02/2021)
8.	Wang, Mengjie: 1 article (02/2021)
9.	Wen, Weihua: 1 article (02/2021)
10.	Pan, Gang: 1 article (01/2019)

Related Diseases

1.	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 02/01/2015 - "Family-based association study of the arsenite methyltransferase gene (AS3MT, rs11191454) in Korean children with attention-deficit hyperactivity disorder." 02/01/2015 - "We examined the association between the selected polymorphisms in two candidate genes, the arsenite methyltransferase gene (AS3MT, rs11191454) and the inter-α-trypsin inhibitors heavy chain-3 gene (ITIH3, rs2535629), and attention-deficit hyperactivity disorder (ADHD) in a Korean population. "
2.	Vaccinia 08/10/2017 - "Researchers have identified and replicated the sharing of susceptible genes, such as within the major histocompatibility complex, microRNA 137 (MIR137), zinc finger protein 804A (ZNF804A), vaccinia related kinase 2 (VRK2), and arsenite methyltransferase (AS3MT), across both European and East Asian populations. "
3.	Schizophrenia (Dementia Praecox) 01/01/2016 - "Here we show that risk alleles spanning multiple genes across the 10q24.32 schizophrenia-related locus are associated in the human brain selectively with an increase in the expression of both BLOC-1 related complex subunit 7 (BORCS7) and a previously uncharacterized, human-specific arsenite methyltransferase (AS3MT) isoform (AS3MT(d2d3)), which lacks arsenite methyltransferase activity and is more abundant in individuals with schizophrenia than in controls. "
4.	Neoplasms (Cancer) 02/01/2021 - "Long-term arsenic exposure can promote cancer through epigenetic mechanisms, and arsenite methyltransferase (AS3MT) plays an important role in this process. "
5.	Type 2 Diabetes Mellitus (MODY) 01/01/2022 - "To evaluate the association between type 2 diabetes mellitus (T2DM) prevalence with arsenic exposure and metabolism, considering one-carbon metabolism nutrient intake and arsenite methyltransferase (AS3MT) polymorphisms. "

Related Drugs and Biologics

1.	Arsenic
2.	Arsenate Reductases (Arsenate Reductase (Azurin))
3.	MicroRNAs (MicroRNA)
4.	Protein Isoforms (Isoforms)
5.	Trypsin Inhibitors
6.	Proteins (Proteins, Gene)
7.	Phosphotransferases (Kinase)
8.	Carbon