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OPC 20011
an oxaisocephem antibiotic; incorrect structure given in first source
Also Known As:
OPC-20011
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Lactams: 2198
OPC 20011: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Lactams: 2198
OPC 20011: 1
Related Diseases
1.
Respiratory Tract Infections (Respiratory Tract Infection)
11/01/1998 - "
OPC-20011 produced a significant decrease of viable counts in lung tissue at a dose of 2.5 mg/kg of body weight, an efficacy similar to that of ampicillin at a dose of 10 to 20 mg/kg on an experimental murine model of respiratory tract infection caused by non-ampicillin-susceptible S.
"
2.
Infections
11/01/1998 - "
The in vivo activities of OPC-20011 were comparable to or greater than those of reference compounds in murine models of systemic infection caused by gram-positive and -negative pathogens.
"
11/01/1998 - "
OPC-20011 was up to 10 times as effective as vancomycin against MRSA infections in mice.
"
3.
Body Weight (Weight, Body)
11/01/1998 - "
OPC-20011 produced a significant decrease of viable counts in lung tissue at a dose of 2.5 mg/kg of body weight, an efficacy similar to that of ampicillin at a dose of 10 to 20 mg/kg on an experimental murine model of respiratory tract infection caused by non-ampicillin-susceptible S.
"
Related Drugs and Biologics
1.
Vancomycin
2.
Ampicillin (Omnipen)