|1.||Sandjo, Louis P: 1 article (01/2015)|
|2.||Ngadjui, Bonaventure: 1 article (01/2015)|
|3.||Seukep, Jackson A: 1 article (01/2015)|
|4.||Efferth, Thomas: 1 article (01/2015)|
|5.||Mbaveng, Armelle T: 1 article (01/2015)|
|6.||Kuete, Victor: 1 article (01/2015)|
|7.||Zeino, Maen: 1 article (01/2015)|
|8.||Youn, Seog Hyeon: 1 article (01/2012)|
|9.||Thuong, Phuong Thien: 1 article (01/2012)|
|10.||Kim, Je Ryong: 1 article (01/2012)|
01/01/2012 - "Pomolic acid (PA) has been previously described as being active in inhibiting the growth of cancer cells. "
01/01/2015 - "This work was designed to assess the cytotoxicity of the methanol crude extracts and compounds from the fruits of Uapaca togoensis, namely, β-amyryl acetate (1), 11-oxo-α-amyryl acetate (2), lupeol (3), pomolic acid (4), futokadsurin B (5), arborinin (6), and 3-O-β-D-glucopyranosyl sitosterol (7) against nine drug sensitive and multidrug-resistant cancer cell lines. "
|2.||BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/01/2007 - "Pomolic acid-induced apoptosis in cells from patients with chronic myeloid leukemia exhibiting different drug resistance profile."
12/01/2007 - "Pomolic acid (PA) is a pentacyclic triterpene which has been previously described as active in inhibiting the growth of K562 cell line-originated from chronic myeloid leukemia (CML) in blast crisis-and its vincristine-resistant derivative K562-Lucena1. "
|3.||Melanoma (Melanoma, Malignant)
02/28/2005 - "In a previous paper, we showed that pomolic acid (PA) is able to kill the leukemia cell line K562 and its MDR derivative, Lucena 1. Here, we demonstrated that PA-induced apoptosis of HL-60 cells is dependent on the activation of caspases-3 and -9 and dissipation of the mitochondrial transmembrane potential (Deltapsim). "
02/28/2005 - "Pomolic acid triggers mitochondria-dependent apoptotic cell death in leukemia cell line."
|5.||Hepatocellular Carcinoma (Hepatoma)
02/01/2004 - "Activity-guided fractionation of the EtOAc-soluble extract of the stems of Couepia ulei, using a bioassay based on the induction of quinone reductase (QR) in cultured Hepa 1c1c7 mouse hepatoma cells led to the isolation of two active compounds, a new natural product, erythro-2,3-bis(4-hydroxy-3-methoxyphenyl)-3-ethoxypropan-1-ol (1), and a known compound, evofolin-B (2), along with five inactive compounds all of known structure, viz., betulinic acid, oleanolic acid, pomolic acid, (+/-)-syringaresinol, and ursolic acid. "
|1.||AMP-Activated Protein Kinases
|3.||NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
|9.||2,5-dichloro-4-bromophenol (B 2)