symplostatin 1

from marine cyanobacterium, Symploca hydnoides; structure in first source

Networked: 3 relevant articles (2 outcomes, 0 trials/studies)

1.	Luesch, Hendrik: 2 articles (03/2015 - 04/2003)
2.	Engene, Niclas: 1 article (03/2015)
3.	Paul, Valerie J: 1 article (03/2015)
4.	Salvador-Reyes, Lilibeth A: 1 article (03/2015)
5.	Corbett, Thomas H: 1 article (04/2003)
6.	Leal, Rachel M: 1 article (04/2003)
7.	Mooberry, Susan L: 1 article (04/2003)
8.	Moore, Richard E: 1 article (04/2003)
9.	Tinley, Tina L: 1 article (04/2003)
10.	Corbett, T H: 1 article (07/2001)

1.	Neoplasms (Cancer) 04/20/2003 - "Symplostatin 1 is a potent inhibitor of cell proliferation with IC(50) values in the low nanomolar range and it exhibits efficacy against a variety of cancer cell types. " 07/01/2001 - "Symplostatin 1 (2) was effective against a drug-insensitive mammary tumor and a drug-insensitive colon tumor; however, it was only slightly effective against two MDR tumors."
2.	Colonic Neoplasms (Colon Cancer) 03/27/2015 - "We found that largazole was always coproduced with dolastatin 10 or with symplostatin 1 and consequently tested combinations of these agents against colon cancer cells. "