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SNX 482

from venom of tarantula, Hysterocrates gigas; amino acid sequence in first source

Also Known As:

SNX-482

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Arthropod Venoms: 770
    - Spider Venoms: 129
      - SNX 482: 3
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Arthropod Venoms: 770
      - Spider Venoms: 129
        SNX 482: 3

Experts

1.	Ferreira, Juliano: 1 article (01/2021)
2.	Ferreira, Marcella Amorim: 1 article (01/2021)
3.	Lückemeyer, Débora Denardin: 1 article (01/2021)
4.	Macedo-Júnior, Sérgio José: 1 article (01/2021)
5.	Prudente, Arthur Silveira: 1 article (01/2021)
6.	Schran, Roberta Giusti: 1 article (01/2021)
7.	Silva, Ana Merian: 1 article (01/2021)
8.	Tonello, Raquel: 1 article (01/2021)
9.	Bee, Lucy A: 1 article (06/2007)
10.	Dickenson, Anthony H: 1 article (06/2007)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 06/01/2007 - "The Cav2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain."
2.	Hyperalgesia 01/01/2021 - "In female but not male mice, intrathecal treatment with the Cav2.3 inhibitor SNX-482 partially and briefly reversed secondary hyperalgesia at a dose (300 pmol/site) that did not cause adverse effects. "
3.	Cardiac Arrhythmias (Arrythmia) 01/01/2004 - "In isolated hearts from wild type mice, arrhythmia was induced by superfusion with a solution containing 200 nM SNX-482, a blocker of some R-type voltage gated Ca2+ channels, suggesting that R-type channels containing the splice variant Cav2.3e as ion conducting pore stabilize a more regular heart beat in prenatal mice."

Related Drugs and Biologics

1.	Solutions
2.	Calcium Channel Blockers (Blockers, Calcium Channel)