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aureolysin

member of the thermolysin family of zinc-dependent metalloproteinases; isolated from Staphylococcus aureus; amino acid sequence in first source

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Bacterial Proteins: 394
    - aureolysin: 6
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Metalloproteases: 8276
        Metalloendopeptidases: 70
        aureolysin: 6
      - Endopeptidases: 633
        Metalloendopeptidases: 70
        aureolysin: 6

Experts

1.	Al Djaizani, Sahra: 1 article (01/2020)
2.	Anderl, Anita: 1 article (01/2020)
3.	Bose, Jeffrey L: 1 article (01/2020)
4.	Daly, Seth M: 1 article (01/2020)
5.	Fiebig, David: 1 article (01/2020)
6.	Fuchsbauer, Hans-Lothar: 1 article (01/2020)
7.	Hall, Pamela R: 1 article (01/2020)
8.	Kolmar, Harald: 1 article (01/2020)
9.	Ridder, Miranda J: 1 article (01/2020)
10.	Seawell, Nichole A: 1 article (01/2020)

Related Diseases

1.	Atopic Dermatitis (Atopic Eczema) 01/01/2014 - "to study the heterogeneity of internal fragments of the aur gene coding a proteolytic enzyme aureolysin in strains of Staphylococcus aureus with different enzymatic activity, which were allocated with the affected skin of patients with atopic dermatitis. "
2.	Infections 11/25/2022 - "Hyperglycemia in Diabetic Skin Infections Promotes Staphylococcus aureus Virulence Factor Aureolysin: Visualization by Molecular Imaging." 06/12/2013 - "(2013) develop a high-resolution microcomputed tomography (microCT) method to visualize bone remodeling during S. aureus infection and discover that the metalloprotease aureolysin plays a critical role in modulating osteomyelitis pathogenesis." 01/01/2020 - "We previously demonstrated that the inactivation of fakA leads to decreased α-hemolysin (Hla) production but increased expression of the proteases SspAB and aureolysin in vitro, and that the ΔfakA mutant causes larger lesions than the wild type (WT) during murine skin infection. "
3.	Osteomyelitis 06/12/2013 - "(2013) develop a high-resolution microcomputed tomography (microCT) method to visualize bone remodeling during S. aureus infection and discover that the metalloprotease aureolysin plays a critical role in modulating osteomyelitis pathogenesis."
4.	Hyperglycemia 11/25/2022 - "Hyperglycemia in Diabetic Skin Infections Promotes Staphylococcus aureus Virulence Factor Aureolysin: Visualization by Molecular Imaging."
5.	Autolysis 01/01/2020 - "Dissecting capture and twisting of aureolysin and pseudolysin: functional amino acids of the Dispase autolysis-inducing protein."

Related Drugs and Biologics

1.	Peptide Hydrolases (Proteases)
2.	Serine Proteases (Serine Protease)
3.	Cysteine Proteases (Cysteine Protease)
4.	Metalloproteases (Metalloproteinases)
5.	Virulence Factors (Pathogenicity Factors)
6.	Proteins (Proteins, Gene)
7.	Hemolysin Proteins (Hemolysins)
8.	Amino Acids
9.	dispase