paclitaxel-transferrin

paclitaxel is a natural product from the bark of the pacific yew it was derivatized on 2' carbon and coupled with transferrin using glutaraldehyde

Also Known As:

paclitaxel, transferrin

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 02/28/2014 - "In vivo antitumor efficacy studies using mice inoculated with KB cells demonstrate significantly higher tumor inhibition rate of 45.1% for paclitaxel-transferrin formulation compared to 28.8% for paclitaxel nanosuspension treatment alone. " 02/28/2014 - "Interestingly, the Taxol(®) formulation showed higher antitumor activity than the paclitaxel-transferrin formulation, achieving a 93.3% tumor inhibition rate 12days post initial dosing. "
2.	Body Weight (Weight, Body) 02/28/2014 - "However, the paclitaxel-transferrin formulation showed a lower level of toxicity, which is indicated by a steady increase in body weight of mice over the treatment period. "

1.	Paclitaxel (Taxol)