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lonafarnib (SCH 66336)

inhibitor of farnesyl protein transferase; structure in first source
Also Known As:
SCH 66336; (+)4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide; 4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide; SCH66336; 1-Piperidinecarboxamide, 4(2-(4-(11R-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine-11-yl)-1-piperidinyl)-2-oxoethyl)-
Networked: 85 relevant articles (10 outcomes, 40 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lee, Ho-Young: 7 articles (08/2012 - 08/2003)
2. Statkevich, Paul: 7 articles (11/2011 - 05/2004)
3. Khuri, Fadlo R: 7 articles (03/2008 - 05/2004)
4. Zhu, Yali: 6 articles (11/2011 - 05/2004)
5. Kirschmeier, Paul: 6 articles (12/2009 - 05/2004)
6. Bishop, W Robert: 6 articles (12/2009 - 01/2003)
7. Kirschmeier, P: 5 articles (09/2008 - 04/2000)
8. Bishop, W R: 5 articles (03/2001 - 01/2000)
9. Kim, Edward S: 4 articles (08/2012 - 05/2004)
10. Long, Brian J: 4 articles (12/2009 - 09/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Carcinoma (Carcinomatosis)
3. Ovarian Neoplasms (Ovarian Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Leukemia

Related Drugs and Biologics

1. Farnesyltranstransferase (Farnesyltransferase)
2. Paclitaxel (Taxol)
3. Hormones
4. taxane
5. Taxoids
6. docetaxel (Taxotere)
7. Protein-Tyrosine Kinases (Tyrosine Kinase)
8. lonafarnib (SCH 66336)
9. Transferases
10. gemcitabine

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Molecular Targeted Therapy
4. Oral Administration
5. Therapeutics