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dimethylaminoethyl chloride

dimethylamine precursor

Also Known As:

2-dimethylaminoethylchloride; DMAEC; N,N-dimethylaminoethyl chloride

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - dimethylaminoethyl chloride: 2

Related Diseases

1.

Body Weight (Weight, Body)

11/01/1998 - "The oral administration of equimolar amounts (1 mmol/kg body weight) of potential amine precursors to male Wistar rats produced only small increases in urinary dimethylamine after choline (+ 11%; 0.60 +/- 0.36% dose), dimethylaminopropanol (+ 32%; 1.49 +/- 0.30% dose), dimethylaminoethyl chloride (+ 110% 5.38 +/- 1.72% dose) and trimethylamine (+ 51%; 1.6 +/- 0.80% dose) input, whereas significantly larger increases were found following trimethylamine N-oxide ingestion (+ 355%; 12.93 +/- 1.13% dose; t-test, P < 0.001). "
01/01/1989 - "Water, choline, dimethylaminoethanol, diethylaminoethanol, phosphocholine, betaine, carnitine, beta-methylcholine or dimethylaminoethyl chloride were administered by orogastric intubation, and the urine was collected for 24 hr. Administration of choline (15 mmol/kg body weight) resulted in increased urinary excretion of dimethylamine, trimethylamine and trimethylamine oxide (increases of approximately twofold, 500-fold and 50-fold, respectively). "

Related Drugs and Biologics

1.	Choline (Choline Chloride)
2.	dimethylamine (dimethylamine nitrate)
3.	trimethylamine
4.	trimethyloxamine (trimethylamine N-oxide)
5.	Phosphorylcholine (Phosphocholine)
6.	Deanol (Dimethylethanolamine)
7.	Carnitine (L-Carnitine)
8.	Betaine (C.B.B.)
9.	Amines
10.	dimethylaminopropanol

Related Therapies and Procedures

1.	Oral Administration