|1.||Hirano, Y: 3 articles (09/2001 - 07/2000)|
|2.||Miyata, K: 3 articles (09/2001 - 07/2000)|
|3.||Kimoto, A: 3 articles (09/2001 - 07/2000)|
|4.||Yamada, T: 3 articles (09/2001 - 07/2000)|
|5.||Iwai, T: 3 articles (09/2001 - 07/2000)|
|6.||Saito, M: 2 articles (09/2001 - 07/2000)|
|7.||Tomioka, K: 2 articles (12/2000 - 07/2000)|
|8.||Saitou, M: 1 article (12/2000)|
12/01/2000 - "These results suggest that YM-40461 ameliorates MCT dysfunction in animals with SO2 gas-induced bronchitis by increasing the DSPC-to-protein ratio in the airway."
12/01/2000 - "Repeated doses of YM-40461 improved the MCT guinea pigs with bronchitis within 5 d after the completion of SO2 exposure, with an ED50 value of 3.1 mg/kg p.o. "
12/01/2000 - "The effects of the surfactant secretagogue YM-40461 on the mucociliary transport (MCT) velocity were examined in guinea pigs with induced bronchitis. "
12/01/2000 - "YM-40461 improves airway clearance in guinea pigs with induced subacute bronchitis."
09/01/2001 - "These results suggest that YM-40461 ameliorates chronic obstructive pulmonary disease (COPD)-like symptoms in bronchitis models due to increased surfactant in the airway."
|2.||Chronic Obstructive Pulmonary Disease (COPD)
|4.||Obstructive Lung Diseases (Obstructive Lung Disease)
09/01/2001 - "Effect of YM-40461, a novel surfactant secretagogue, on chronic obstructive pulmonary diseases and similar symptoms in guinea pigs."
07/01/1998 - "These results may indicate that YM-26818 is useful for the therapy of adult respiratory distress syndrome (ARDS) and obstructive pulmonary diseases."
|5.||Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
|2.||Pulmonary Surfactants (Pulmonary Surfactant)