HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

YM 26818

Also Known As:

1-(2-dimethylaminoethyl)-1-(3,4,5-trimethoxyphenyl)urea; YM-26818; YM-40461

Networked: 4 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Phenylurea Compounds: 1
      - YM 26818: 4
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenylurea Compounds: 1
        YM 26818: 4

Experts

1.	Hirano, Y: 3 articles (09/2001 - 07/2000)
2.	Iwai, T: 3 articles (09/2001 - 07/2000)
3.	Kimoto, A: 3 articles (09/2001 - 07/2000)
4.	Miyata, K: 3 articles (09/2001 - 07/2000)
5.	Yamada, T: 3 articles (09/2001 - 07/2000)
6.	Saito, M: 2 articles (09/2001 - 07/2000)
7.	Tomioka, K: 2 articles (12/2000 - 07/2000)
8.	Saitou, M: 1 article (12/2000)

Related Diseases

1.	Bronchitis 12/01/2000 - "Repeated doses of YM-40461 improved the MCT guinea pigs with bronchitis within 5 d after the completion of SO2 exposure, with an ED50 value of 3.1 mg/kg p.o. " 12/01/2000 - "YM-40461 improves airway clearance in guinea pigs with induced subacute bronchitis." 12/01/2000 - "These results suggest that YM-40461 ameliorates MCT dysfunction in animals with SO2 gas-induced bronchitis by increasing the DSPC-to-protein ratio in the airway." 09/01/2001 - "These results suggest that YM-40461 ameliorates chronic obstructive pulmonary disease (COPD)-like symptoms in bronchitis models due to increased surfactant in the airway." 12/01/2000 - "The effects of the surfactant secretagogue YM-40461 on the mucociliary transport (MCT) velocity were examined in guinea pigs with induced bronchitis. "
2.	Chronic Obstructive Pulmonary Disease (COPD) 09/01/2001 - "These results suggest that YM-40461 ameliorates chronic obstructive pulmonary disease (COPD)-like symptoms in bronchitis models due to increased surfactant in the airway." 09/01/2001 - "Effect of YM-40461, a novel surfactant secretagogue, on chronic obstructive pulmonary diseases and similar symptoms in guinea pigs."
3.	Hypoxia (Hypoxemia) 09/01/2001 - "A dose of 10 mg/kg of YM-40461 relieved hypoxemia in these animals with the values returning to 81.8 +/- 1.9 cm H2O (p < 0.05). "
4.	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 07/01/1998 - "These results may indicate that YM-26818 is useful for the therapy of adult respiratory distress syndrome (ARDS) and obstructive pulmonary diseases."
5.	Obstructive Lung Diseases (Obstructive Lung Disease) 07/01/1998 - "These results may indicate that YM-26818 is useful for the therapy of adult respiratory distress syndrome (ARDS) and obstructive pulmonary diseases."

Related Drugs and Biologics

1.	Surface-Active Agents (Surfactants)
2.	Proteins (Proteins, Gene)
3.	Secretagogues
4.	Urea (Carbamide)
5.	Pulmonary Surfactants (Pulmonary Surfactant)

Related Therapies and Procedures

1.	Therapeutics