rat endothelial barrier antigen

a monoclonal antibody is expressed in rat cerebral microvessels possessing blood-brain barrier properties but only weakly by fenestrated vessels

Also Known As:

endothelial barrier antigen, rat; antigen, endothelial barrier; endothelial barrier antigen

Networked: 19 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - rat endothelial barrier antigen: 19

Experts

1.	Lo, Eng H: 2 articles (12/2017 - 05/2004)
2.	Wang, Xiaoying: 2 articles (12/2017 - 05/2004)
3.	Ginsberg, M D: 2 articles (04/2001 - 05/2000)
4.	Lin, B: 2 articles (04/2001 - 05/2000)
5.	Bernal-Teran, Edson G: 1 article (01/2019)
6.	Bitterfeld, Leandra: 1 article (01/2019)
7.	Carmen-Orozco, Rogger P: 1 article (01/2019)
8.	Cauna, Yudith: 1 article (01/2019)
9.	Chile, Nancy: 1 article (01/2019)
10.	Céliz, Rensson H: 1 article (01/2019)

Related Diseases

1.	Stroke (Strokes) 02/09/2007 - "All rats were sacrificed 6 weeks after stroke and endothelial barrier antigen immunostaining was employed for morphological analysis and quantification of cerebral vessels. " 12/01/2017 - "At 16 h after stroke onset, the combination therapy significantly reduced BBB disruption, and improved preservation of the junction proteins ZO-1 and ve-cadherin, decreased activation of matrix metalloproteinase, inhibited degradation of extracellular matrix collagen IV and endothelial barrier antigen, and reduced microglia/macrophage and astrocytes activations. " 12/01/2017 - "At an earlier time point, 16 h after stroke, BBB integrity was evaluated by IgG extravasation, and the involved mechanisms were assessed for tight junction ZO-1 and adhesion junction ve-cadherin protein expression, matrix metalloproteinase activation, extracellular matrix collagen IV and endothelial barrier antigen expression, and activation of microglia/macrophages and astrocytes. "
2.	Embolic Stroke 12/18/2013 - "Endothelial barrier antigen-immunoreactivity is conversely associated with blood-brain barrier dysfunction after embolic stroke in rats." 12/18/2013 - "This study aimed to characterize the endothelial barrier antigen (EBA) as addressed by the antibody SMI-71 in a rat model of embolic stroke, considering FITC-albumin as BBB leakage marker and serum levels of BBB-associated matrix metalloproteinases (MMPs) to explore its functional significance. "
3.	Herpes Zoster 05/01/2004 - "At 3-24 hours, immunoreactive laminin, endothelial barrier antigen, and zona occludens-1 diminished in the ipsilateral cortex, suggesting that CSD altered proteins critical to the integrity of the BBB. " 10/01/2008 - "In order to clarify the nature of the BBB in the median eminence-arcuate nucleus complex, we have used immunohistochemistry and antisera to protein components of the BBB-(1) tight junctions, claudin-5 and zona occludens-1 (ZO-1); (2) endothelial cells: (a) all endothelial cells: rat endothelial cell antigen-1 (RECA-1), (b) endothelial cells at BBB: endothelial barrier antigen (EBA), glucose transporter 1 (GLUT1) and transferrin receptor (TfR), and (c) endothelial cells at CVOs: dysferlin; (3) basal lamina: laminin; (4) vascular smooth muscle cells: smooth muscle actin (SMA); (5) pericytes: chondroitin sulfate proteoglycan (NG2); (6) glial cells: (a) astrocytes: glial fibrillary acidic protein (GFAP), (b) tanycytes: dopamine- and cAMP-regulated phosphoprotein of 32kDA (DARPP-32), (c) microglia: CD11b. "
4.	Dyskinesias (Dyskinesia) 11/01/2009 - "L-DOPA, but not bromocriptine, induced dyskinesia, which was associated with endothelial proliferation, upregulation of immature endothelial markers (nestin) and downregulation of endothelial barrier antigen in the striatum and its output structures. "
5.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 04/01/2005 - "This method was applied to different immunostaining antibodies, such as endothelial barrier antigen (EBA), lectin, and glial fibrillary acidic protein (GFAP), on histology slides from animals subjected to middle cerebral artery occlusion by the intraluminal suture method. "

Related Drugs and Biologics

1.	Matrix Metalloproteinases (MMPs)
2.	Proteins (Proteins, Gene)
3.	Collagen
4.	cadherin 5
5.	FITC-albumin
6.	Laminin (Merosin)
7.	Facilitative Glucose Transport Proteins (Glucose Transporter)
8.	Immunoglobulin G (IgG)
9.	Glial Fibrillary Acidic Protein
10.	Nestin

Related Therapies and Procedures

1.	Therapeutics
2.	Sutures (Suture)