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2-butylamino-2-demethoxy-hypocrellin A
structure in first source
Also Known As:
2-BA-2-DMHA; BAHA cpd
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Anthracenes: 12
Perylene: 61
2-butylamino-2-demethoxy-hypocrellin A: 4
Phenalenes: 1
Perylene: 61
2-butylamino-2-demethoxy-hypocrellin A: 4
Quinones: 434
2-butylamino-2-demethoxy-hypocrellin A: 4
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Anthracenes: 12
Perylene: 61
2-butylamino-2-demethoxy-hypocrellin A: 4
Phenalenes: 1
Perylene: 61
2-butylamino-2-demethoxy-hypocrellin A: 4
Experts
1.
Yang, Hongying
: 1 article (02/2003)
2.
Zhang, Zhiyi
: 1 article (02/2003)
3.
Zhou, Zhixiang
: 1 article (02/2003)
Related Diseases
1.
Phototoxic Dermatitis (Phototoxicity)
06/15/1998 - "
The mechanism of phototoxicity of 2-BA-2-DMHA on MGC803 cells irradiated with red light (lamada = 600-700 nm) has also been studied.
"
06/15/1998 - "
1. Synthesis of 2-BA-2-DMHA and its phototoxicity to MGC803 cells.
"
04/26/1999 - "
Wild-type p53 protein potentiates phototoxicity of 2-BA-2-DMHA in HT29 cells expressing endogenous mutant p53.
"
02/17/2003 - "
Role of calcium in phototoxicity of 2-butylamino-2-demethoxy-hypocrellin A to human gastric cancer MGC-803 cells.
"
05/01/1999 - "
The decreased expression of bcl-2 protein was accompanied by increased phototoxicity and susceptibility to apoptosis induced by 2-BA-2-DMHA PDT.
"
2.
Photosensitivity Disorders (Photodermatitis)
04/26/1999 - "
The influence of p53 status on the sensitivity induced by 2-butylamino-2-demethoxy-hypocrellin A (2-BA-2-DMHA) photosensitization was then examined.
"
02/17/2003 - "
Fluorescence spectrophotometry measurement indicated that the photosensitization of MGC-803 by 2-BA-2-DMHA caused an increase in intracellular calcium [Ca(2+)](i), and this increase in [Ca(2+)](i) showed a dependence on the concentration of 2-BA-2-DMHA, light dose and extracellular [Ca(2+)](e).
"
05/01/1999 - "
Here we investigated the effect of an antisense bcl-2 RNA retrovirus vector transfer on the sensitivity of 2-butylamino-2-demethoxy-hypocrellin A (2-BA-2-DMHA) photosensitization in a human gastric adenocarcinoma MGC803 cell line.
"
3.
Stomach Neoplasms (Stomach Cancer)
02/17/2003 - "
After incubation with 2-butylamino-2-demethoxy-hypocrellin A (2-BA-2-DMHA), photodynamically induced change in the cytoplasmic free calcium concentration ([Ca(2+)](i)) and its effect on cell damage were investigated in human gastric cancer (MGC-803).
"
02/17/2003 - "
Role of calcium in phototoxicity of 2-butylamino-2-demethoxy-hypocrellin A to human gastric cancer MGC-803 cells.
"
4.
Adenocarcinoma
05/01/1999 - "
Here we investigated the effect of an antisense bcl-2 RNA retrovirus vector transfer on the sensitivity of 2-butylamino-2-demethoxy-hypocrellin A (2-BA-2-DMHA) photosensitization in a human gastric adenocarcinoma MGC803 cell line.
"
Related Drugs and Biologics
1.
Proteins (Proteins, Gene)
2.
RNA (Ribonucleic Acid)
3.
Calcium
4.
1-phenyl-3,3-dimethyltriazene (PDT)