sublancin 168

10/04/2017 - "This study was performed to evaluate the efficacy of sublancin in the prevention of MRSA ATCC43300 intraperitoneal infection in mice. "
01/01/2019 - "In this study, we investigated the role and anti-infection mechanism of sublancin in a mouse model of MRSA-induced sublethal infection. "
01/01/2021 - "These results demonstrates that sublancin stimulates the innate response and modulates the microbiota community to protect against MRSA infection."
01/01/2021 - "We further show that sublancin exhibits protection in a mouse MRSA infection model. "
01/01/2021 - "Sublancin protects against methicillin-resistant Staphylococcus aureus infection by the combined modulation of innate immune response and microbiota."

10/01/2015 - "The antimicrobial peptide sublancin ameliorates necrotic enteritis induced by Clostridium perfringens in broilers."
10/01/2015 - "These novel findings indicate that sublancin could be used as a potential antimicrobial agent to control necrotic enteritis. "
10/01/2015 - "In conclusion, although sublancin's minimum inhibitory concentration is much higher than lincomycin in vitro, less sublancin is needed to control necrotic enteritis induced by in vivo than lincomycin. "

01/01/2019 - "This study was aimed at investigating the effects of sublancin on immune functions and serum antibody titer in specific pathogen-free (SPF) broiler chickens vaccinated with Newcastle disease (ND) vaccine. "
01/01/2019 - "A Novel Adjuvant "Sublancin" Enhances Immune Response in Specific Pathogen-Free Broiler Chickens Inoculated with Newcastle Disease Vaccine."

01/01/2018 - "In normal mice, the phagocytic activity of mouse peritoneal macrophages was significantly enhanced by oral administration of sublancin (1.0 mg/kg body weight) to BALB/c mice for 7 days (P < 0.01). "
01/01/2018 - "In addition, the mRNA expression of IL-1β, IL-6, and TNF-α in peritoneal macrophages from sublancin- (1.0 mg/kg body weight) administered mice was significantly increased (P < 0.05). "
08/01/2014 - "Mice in the other seven groups were injected intraperitoneally with 0.5 mL of 0.9% saline containing 0, 0.5, 1.0, 2.0, or 4.0 mg/kg body weight (BW) sublancin or 1.0 or 2.0 mg/kg BW ampicillin. "

10/04/2017 - "With their combined antibacterial and immunomodulatory activities, sublancin may have potent therapeutic potential for drug-resistant infections and sepsis."