a trifluoromethyl ketone-based; structure in first source
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Bio-Agent Context: Research Results
|1. ||Chronic Obstructive Pulmonary Disease (COPD)
- "ZD-0892, a neutrophil elastase inhibitor, is under development by AstraZeneca as a potential treatment for chronic obstructive pulmonary disease (COPD) and peripheral vascular disease (PVD).
- "In the application of chronic obstructive pulmonary disease therapy, the human neutrophil elastase inhibitors mainly focused upon include ONO-5046, MR-889, L-694,458, CE-1037, GW-311616 and TEI-8362 as the acyl-enzyme inhibitors; and ONO-6818, AE-3763, FK-706, ICI-200,880, ZD-0892 and ZD-8321 as the transition-state inhibitors.
|2. ||Peripheral Vascular Diseases (Peripheral Vascular Disease)
|3. ||Pulmonary Hypertension (Ayerza Syndrome)
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