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N-propionyl-4-S-cysteaminylphenol

antimelanoma agent, a biochemical pathway operating only in melanoma cells so that the tumour can be targeted

Also Known As:

N-P-C phenol

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Cystamine: 222
      - N-propionyl-4-S-cysteaminylphenol: 7
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        N-propionyl-4-S-cysteaminylphenol: 7

Experts

1.	Honda, Hiroyuki: 4 articles (01/2013 - 09/2010)
2.	Ito, Akira: 4 articles (01/2013 - 09/2010)
3.	Ito, Shosuke: 4 articles (01/2013 - 09/2010)
4.	Jimbow, Kowichi: 4 articles (01/2013 - 09/2010)
5.	Tamura, Yasuaki: 4 articles (01/2013 - 09/2010)
6.	Wakamatsu, Kazumasa: 4 articles (01/2013 - 09/2010)
7.	Yamashita, Toshiharu: 4 articles (01/2013 - 09/2010)
8.	Ishii-Osai, Yasue: 3 articles (01/2013 - 07/2012)
9.	Nakayama, Eiichi: 3 articles (01/2013 - 07/2012)
10.	Okura, Masae: 2 articles (07/2012 - 09/2010)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 07/01/2012 - "N-propionyl-4-S-cysteaminylphenol (NPr-4-S-CAP) is selectively incorporated into melanoma cells and degrades them. " 07/01/2012 - "N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model." 09/01/2010 - "Melanogenesis substrate, N-propionyl-4-S-cysteaminylphenol (NPrCAP) is specifically taken up by melanoma cells and inhibits their growth by producing cytotxic free radicals. " 09/01/2012 - "Mechanism of putative neo-antigen formation from N-propionyl-4-S-cysteaminylphenol, a tyrosinase substrate, in melanoma models." 12/01/1999 - "Sulphur containing substrate (tyrosine) analogs, N-acetyl-4-S-cysteaminylphenol (NAcCAP) and N-propionyl-4-S-cysteaminylphenol (NPrCAP), have been shown to have potent antimelanoma activity in mice bearing melanoma. "
2.	Neoplasms (Cancer) 07/01/2012 - "N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model."
3.	Experimental Melanoma 06/15/1998 - "A 10-day treatment with N-propionyl-4-S-cysteaminylphenol at 300 mg/kg body weight reduced the growth rate of B16 melanoma s.c. "
4.	Body Weight (Weight, Body) 06/15/1998 - "A 10-day treatment with N-propionyl-4-S-cysteaminylphenol at 300 mg/kg body weight reduced the growth rate of B16 melanoma s.c. "

Related Drugs and Biologics

1.	Tyrosine (L-Tyrosine)
2.	Monophenol Monooxygenase (Tyrosinase)
3.	Sulfur
4.	Amines
5.	Melanins (Melanin)
6.	Free Radicals
7.	Enzymes
8.	Antigens
9.	N-acetyl-4-S-cysteaminylphenol