|1.||Brechbiel, Martin W: 8 articles (12/2005 - 07/2002)|
|2.||Torti, Suzy V: 7 articles (12/2005 - 06/2003)|
|3.||Planalp, Roy P: 6 articles (12/2005 - 07/2002)|
|4.||Torti, Frank M: 6 articles (12/2005 - 06/2003)|
|5.||Ma, Rong: 5 articles (12/2005 - 05/2004)|
|6.||Yap, Glenn P A: 1 article (12/2005)|
|7.||Regino, Celeste Aida S: 1 article (12/2005)|
|8.||Kreisel, Kevin A: 1 article (12/2005)|
|9.||Brown, Kevin D: 1 article (11/2005)|
|10.||Kute, Timothy E: 1 article (11/2005)|
11/01/2005 - "Tachpyridine arrested cells at G2, a radiosensitive phase of the cell cycle, and enhanced the sensitivity of cancer cells but not nontransformed cells to ionizing radiation. "
11/01/2005 - "Tachpyridine is a cytotoxic metal chelator with potential anti-tumor activity. "
10/07/2004 - "BOC-protected tachpyr derivative 14 exhibited the most potent cytotoxicity against this cancer cell line, which was reasonably comparable to the parent tachpyr. "
05/01/2004 - "Tachpyridine induces apoptosis in cultured cancer cells by triggering a mitochondrial pathway of cell death that is p53-independent. "
10/01/2001 - "In addition, in 55 human cancer cell lines the mean GI(50) of tachpyridine in cells with mutant p53 was virtually identical to the GI(50) in cells with wild-type p53. "
|2.||Urinary Bladder Neoplasms (Bladder Cancer)
08/15/1998 - "When added to MBT2 or T24 cultured bladder cancer cells, tachpyr was profoundly cytotoxic, with an IC50 of approximately 4.6 micromol/L compared with 70 micromol/L for desferioxamine. "
07/03/2002 - "Tachpyr (N,N'N"-tris(2-pyridylmethyl)-cis,cis-1,3,5-triaminocyclohexane), a novel metal chelator, was previously shown to deplete intracellular iron and exert a cytotoxic effect on cultured bladder cancer cells. "
|3.||Lung Neoplasms (Lung Cancer)
|5.||Ataxia Telangiectasia (Louis Bar Syndrome)
|9.||Etoposide (VP 16)