cytochrome P-450 CYP3A14 (guinea pig)

member of the CYP3A subfamily isolated from male guinea pig liver; highly homologous to CYP3A20 but expression is differently regulated; amino acid sequence in first source; oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics

Also Known As:

CYP3A14; CYPIIIA14; cytochrome P-450 CYP3A14

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxygenases: 333
      - Mixed Function Oxygenases: 2175
        Cytochrome P-450 Enzyme System: 5365
        Aryl Hydrocarbon Hydroxylases: 18
        cytochrome P-450 CYP3A14 (guinea pig): 1
- Cytochromes: 2196
  - Cytochrome P-450 Enzyme System: 5365
    - Aryl Hydrocarbon Hydroxylases: 18
      - cytochrome P-450 CYP3A14 (guinea pig): 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Hemeproteins: 194
    - Cytochromes: 2196
      - Cytochrome P-450 Enzyme System: 5365
        Aryl Hydrocarbon Hydroxylases: 18
        cytochrome P-450 CYP3A14 (guinea pig): 1

Related Diseases

1.	Argininosuccinic Aciduria 12/15/1997 - "In fact, the level of mRNA for CYP3A14 was unaffected by the AsA deficiency, while those for CYP3A15 and CYP3A17 were significantly decreased by the AsA deficiency, clearly indicating that the expression of each isozyme within the CYP3A subfamily is differently regulated by AsA. "

Related Drugs and Biologics

1.	Cytochrome P-450 CYP3A
2.	Messenger RNA (mRNA)
3.	Isoenzymes