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sulfo Lewis C

a putative ligand for selectins; selectin blockade attenuated lung injury after smoke exposure

Also Known As:

SO3(-3)-Gal(1-3)GlcNAc-O(CH2)8-COOMe; sulfo-Lewis C

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Blood Group Antigens: 5213
      - Lewis Blood Group Antigens: 208
        sulfo Lewis C: 3
  - Isoantigens: 1221
    - Blood Group Antigens: 5213
      - Lewis Blood Group Antigens: 208
        sulfo Lewis C: 3
Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - sulfo Lewis C: 3

Related Diseases

1.	Smoke Inhalation Injury 07/01/1998 - "Effect of Sulfo Lewis C on smoke inhalation injury in an ovine model." 07/01/1998 - "Effect of Sulfo Lewis C on smoke inhalation injury." 07/01/1998 - "To evaluate the effect of Sulfo Lewis C (SO3-3âGal1-3GlcNAc-O(CH2)8-COOMe), a putative ligand of selectins, on smoke inhalation injury. "
2.	Lung Injury 06/01/1999 - "Selectin blockade significantly worsened lung injury induced by LPS infusion, and greater numbers of neutrophils were observed in alveolar spaces in the group treated with Sulfo Lewis C. "
3.	Hypoxia (Hypoxemia) 06/01/1999 - "Hypoxemia, indexed as Pao2/FIO2, was exacerbated by the administration of Sulfo Lewis C (G1:437+/-33 vs. G2: 241+/-63 mm Hg at 5 hours, p<0.03). "

Related Drugs and Biologics

1.	Selectins
2.	Ligands