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diethyl(2- methyl- 2- pyrrolidinyl)phosphonate

structure in first source

Also Known As:

DEPMPH; diethyl (2-methylpyrrolidin-2-yl)phosphonate

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - diethyl(2-methyl-2-pyrrolidinyl)phosphonate: 2
Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphonates: 424
    - diethyl(2-methyl-2-pyrrolidinyl)phosphonate: 2

Experts

1.	Canioni, P: 1 article (01/2001)
2.	Culcasi, M: 1 article (01/2001)
3.	Delmas-Beauvieux, M C: 1 article (01/2001)
4.	Gallis, J L: 1 article (01/2001)
5.	Martel, S: 1 article (01/2001)
6.	Pietri, S: 1 article (01/2001)

Related Diseases

1.	Pathologic Processes 01/19/2001 - "It was concluded that the highly pH-sensitive DEPMPH could be of great interest in noninvasive ex vivo studies of pH gradients that may be involved in many pathological processes."
2.	Ischemia 01/19/2001 - "The novel phosphorylated pyrrolidine diethyl(2-methylpyrrolidin-2-yl)phosphonate (DEPMPH) was evaluated as a (31)P NMR probe of the pH changes associated with ischemia/reperfusion of rat isolated hearts and livers. " 06/01/1998 - "We therefore compared the effects of perfusing 5 mM of two nitrones, DMPO and 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide (DEPMPO) or the two structurally related pyrrolidines, diethyl (2-methyl-2-pyrrolidinyl) phosphonate (DEPMPH) and pyrrolidine (PyH), on postischemic functional recovery of rat hearts subjected to 10 min of low-flow ischemia, 30 min of global ischemia and 60 min of reperfusion. "
3.	Myocardial Ischemia (Ischemic Heart Diseases) 01/19/2001 - "During severe myocardial ischemia, a third peak corresponding to DEPMPH located in ventricular and atrial cavities appeared (pH 6.9). "

Related Drugs and Biologics

1.	pyrrolidine
2.	Organophosphonates (Phosphonates)
3.	Pyrrolidines
4.	Oxides
5.	nitrones