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serotonin 1C receptor
Also Known As:
5-HT(1C)R; 5-HT1C receptor; receptor, serotonin 1C; serotonin 1C receptors
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Membrane Proteins: 10078
Cell Surface Receptors: 2125
G-Protein-Coupled Receptors: 4701
Serotonin Receptors: 1874
serotonin 1C receptor: 6
Neurotransmitter Receptors: 562
Serotonin Receptors: 1874
serotonin 1C receptor: 6
Biogenic Amine Receptors: 8
Serotonin Receptors: 1874
serotonin 1C receptor: 6
Related Diseases
1.
Migraine Disorders (Migraine)
09/01/1991 - "
These findings do not support the theory that 5-HT1C receptor activation causes migraine.
"
08/01/1989 - "
5-HT1C receptor activation: a key step in the initiation of migraine?
"
01/01/1991 - "
It is not yet known which 5-HT1C receptor-mediated actions of 5-HT are relevant to migraine, but some behavioural actions and cranial vasodilatation via release of endothelium-derived relaxing factor may be involved.(ABSTRACT TRUNCATED AT 250 WORDS)
"
2.
Substance Withdrawal Syndrome (Withdrawal Symptoms)
07/01/1993 - "
This effect may be exploited in developing specific 5-HT1C receptor antagonists for the treatment of ethanol withdrawal symptoms.
"
3.
Glioma (Gliomas)
09/05/1996 - "
The 5-HT1C receptor was expressed in six glioma cell lines but not in normal astrocytes while the 5-HT1A was found to be expressed in normal astrocytes from the left hemisphere and in six glioma cell lines but not in normal astrocytes from the cerebellum.
"
4.
Body Weight (Weight, Body)
10/01/1993 - "
To explore the hypothesis that serotonin (5-HT) is important in osmoregulated arginine vasopressin (AVP) secretion, we administered (i.p.) fluoxetine (FL) a 5-HT reuptake inhibitor (10 mg/kg body weight), ritanserin (RIT), an antagonist at the 5-HT2 and 5-HT1c receptor subtypes (1 mg/kg body weight), 1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane hydrochloride (DOI), a 5-HT2 receptor agonist (1 mg/kg body weight) or vehicle to rats 30 min before they were given an osmotic challenge.
"
Related Drugs and Biologics
1.
Serotonin (5 Hydroxytryptamine)
2.
Endothelium-Dependent Relaxing Factors (Endothelium Derived Relaxing Factor)
3.
Ritanserin
4.
Fluoxetine (Prozac)
5.
Arginine Vasopressin (Argipressin)
6.
Ethanol (Ethyl Alcohol)
7.
4-iodo-2,5-dimethoxyphenylisopropylamine (DOI-P)