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NPC 18915
a benzofuran compound, inhibitor of neutophil activation
Also Known As:
NPC-18915
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzoates: 426
NPC 18915: 1
Carboxylic Acids: 973
Carbocyclic Acids
Benzoates: 426
NPC 18915: 1
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzofurans: 26
NPC 18915: 1
Related Diseases
1.
Colitis
01/01/1998 - "
NPC-18915 was effective at significantly reducing colonic injury and granulocyte infiltration in the reactivated colitis model, and a similar effect could be observed in rats treated with antineutrophil serum.
"
01/01/1998 - "
When treatment of NPC-18915 was initiated after colitis was firmly established (48 h posthapten), it did not produce a significant effect.
"
01/01/1998 - "
NPC-18915 given during the first 4 days after induction of acute colitis significantly reduced tissue injury and the incidence of diarrhea and adhesions.
"
01/01/1998 - "
In this study, we have assessed the effects of an inhibitor of neutrophil activation and adherence, NPC-18915 (4-¿2-[2-(2-benzofuranyl)phenyl]-(E)-ethenyl¿benzoic acid sodium salt), in models of both acute and reactivated colitis.
"
2.
Diarrhea
01/01/1998 - "
NPC-18915 given during the first 4 days after induction of acute colitis significantly reduced tissue injury and the incidence of diarrhea and adhesions.
"
Related Drugs and Biologics
1.
Sodium
2.
Salts
3.
Acids