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MP 2269

blood pool contrast agent; structure in first source

Also Known As:

MP-2269; gadolinium 4-pentylbicyclo(2.2.2)octane-1-carboxyl-di-L-aspartyl-lysine-derived-DTPA

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Adams, M D: 1 article (02/2001)
2.	Adzamli, K: 1 article (02/2001)
3.	Cresens, E: 1 article (02/2001)
4.	Marchal, G: 1 article (02/2001)
5.	Miao, Y: 1 article (02/2001)
6.	Ni, Y: 1 article (02/2001)
7.	Periasamy, M P: 1 article (02/2001)
8.	Yu, J: 1 article (02/2001)

Related Diseases

1.	Necrosis 02/01/2001 - "On delayed phase (>60 minutes), a necrosis-specific contrast enhancement (contrast ratio 1.6) developed with gadophrin-2 but not with MP-2269. " 02/01/2001 - "MRI contrast enhancement of necrosis by MP-2269 and gadophrin-2 in a rat model of liver infarction." 02/01/2001 - "Although both MP-2269 and gadophrin-2 feature an albumin-binding capacity, only gadophrin-2 displayed a persistent necrosis-specific contrast enhancement in the rat model of reperfused liver infarction. "
2.	Hepatic Infarction 02/01/2001 - "MRI contrast enhancement of necrosis by MP-2269 and gadophrin-2 in a rat model of liver infarction." 02/01/2001 - "The present MRI-histomorphology correlation study was conducted to verify the likelihood of the proposed albumin-binding mechanism by comparing an albumin-binding blood pool agent, MP-2269, with gadophrin-2 in a rat model of reperfused liver infarction. " 02/01/2001 - "Although both MP-2269 and gadophrin-2 feature an albumin-binding capacity, only gadophrin-2 displayed a persistent necrosis-specific contrast enhancement in the rat model of reperfused liver infarction. "

Related Drugs and Biologics

1.	Albumins
2.	gadophrin-2