C elegans VAB-8 protein

vab-8 gene encodes a novel protein containing an atypical kinesin-like motor domain that is required for many posteriorly-directed cell migrations, as well as axonal outgrowth and pathfinding; vab-8 encodes two protein isoforms: VAB-8S, a novel protein expressed in migrating cells, and VAB-8L, which contains a kinesin-related domain, is expressed in neurons and functions in growth cone migrations; VAB-8 interacts with UNC-51, a serine-threonine kinase also required for axon outgrowth; isolated from Caenorhabditis elegans; amino acid sequence in first source
Also Known As:
VAB-8 protein, C elegans; klp-5 protein, C elegans; unc-107 protein, C elegans
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Bio-Agent Context: Research Results