mekratin

a 26 kDa hamster skeletal muscle neutral protease that cleaves myosin LC2; 63-85% identity with rat & mouse mast cell proteases; amino acid sequence in first source; GenBank AF020767

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        mekratin: 1
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        mekratin: 1

Related Diseases

1.	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 05/01/1999 - "A neutral protease, mekratin, active in human hearts at end stage idiopathic dilated cardiomyopathy (IDC), mediates the breakdown of cardiac myosin LC2. "

Related Drugs and Biologics

1.	Cardiac Myosins
2.	Peptide Hydrolases (Proteases)