UK 1745

RN refers to (2RS,3SR)-isomer; RN & structure in first source

Also Known As:

2-aminomethyl-2,3,7,8-tetrahydro-2,3,5,8,8-pentamethyl-6H-furo(2,3-e)indole-7-one hydrochloride; UK-1745

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Heart Failure 03/01/1998 - "The results suggest that UK-1745 is a novel positive inotropic agent with vasodilatory and antiarrhythmic properties, without significant chronotropic action, and may be beneficial for the treatment of congestive heart failure." 03/01/1998 - "In experimentally induced acute heart failure in anesthetized open-chest dogs, intravenously injected UK-1745 effectively improved hemodynamic functions. "
2.	Ventricular Fibrillation 03/01/1998 - "In mice, orally administered UK-1745 protected the development of ventricular fibrillation induced by chloroform inhalation, whereas vesnarinone did not. "

1.	Chloroform (Trichloromethane)
2.	vesnarinone