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4-phenoxyphenoxyethyl thiocyanate

has antiparasitic activity; structure in first source
Also Known As:
WC-9 compound
Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Rodriguez, Juan B: 4 articles (11/2013 - 08/2002)
2. Docampo, Roberto: 4 articles (11/2013 - 08/2002)
3. Szajnman, Sergio H: 2 articles (11/2013 - 08/2002)
4. Moreno, Silvia N J: 2 articles (11/2013 - 09/2007)
5. Li, Catherine: 1 article (11/2013)
6. Galizzi, Melina: 1 article (11/2013)
7. Chao, María N: 1 article (11/2013)
8. Elicio, Pablo D: 1 article (11/2013)
9. Codesido, Nicolás Osa: 1 article (09/2007)
10. Gismondi, Santiago: 1 article (09/2007)

Related Diseases

1. Chagas Disease (American Trypanosomiasis)
06/01/2003 - "We investigated the molecular basis of the activity of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the etiological agent of Chagas' disease. "
06/01/2003 - "Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease."
08/29/2002 - "As a continuation of our project aimed at the search for new and safe chemotherapeutic and chemoprophylactic agents against American trypanosomiasis (Chagas' disease), several drugs structurally related to 4-phenoxyphenoxyethyl thiocyanate (4) were designed, synthesized, and evaluated as antiproliferative agents against the parasite responsible for this disease, the hemoflagellated protozoan Trypanosoma cruzi. "
11/01/2013 - "As a part of our project pointed at the search of new safe chemotherapeutic and chemoprophylactic agents against parasitic diseases, several compounds structurally related to 4-phenoxyphenoxyethyl thiocyanate (WC-9), which were modified at the terminal aromatic ring, were designed, synthesized and evaluated as antiproliferative agents against Trypanosoma cruzi, the parasite responsible of American trypanosomiasis (Chagas disease) and Toxoplasma gondii, the etiological agent of toxoplasmosis. "
09/15/2007 - "As a part of our project aimed at developing new safe chemotherapeutic and chemoprophylactic agents against tropical diseases, fluorine-containing drugs structurally related to 4-phenoxyphenoxyethyl thiocyanate (1) were designed, synthesized, and evaluated as antiproliferative agents against Trypanosoma cruzi, the parasite responsible of American trypanosomiasis (Chagas' disease), and Toxoplasma gondii, the etiological agent of toxoplasmosis. "
2. Toxoplasmosis
3. Parasitic Diseases (Parasitic Disease)

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