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KR 31080

structure in first source

Also Known As:

2-butyl-5-methyl-6-(1-oxopyridin-2-yl)-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-3H-imidazo(4,5-b)pyridine; KR31080; SK-1080

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Tetrazoles: 14
      - KR 31080: 3
  - Pyridines: 88
    - KR 31080: 3

Experts

1.	Bengel, Frank M: 1 article (12/2010)
2.	Bravo, Paco E: 1 article (12/2010)
3.	Dannals, Robert F: 1 article (12/2010)
4.	Fukushima, Kenji: 1 article (12/2010)
5.	Higuchi, Takahiro: 1 article (12/2010)
6.	Javadi, Mehrbod S: 1 article (12/2010)
7.	Lautamäki, Riikka: 1 article (12/2010)
8.	Mathews, William B: 1 article (12/2010)
9.	Szabo, Zsolt: 1 article (12/2010)
10.	Xia, Jinsong: 1 article (12/2010)

Related Diseases

1.	Hypertension (High Blood Pressure) 03/01/1999 - "These results suggest that SK-1080 is a potent, orally active AT1-receptor antagonist useful for the treatment of hypertension."
2.	Atherosclerosis 10/01/2002 - "These results suggest that SK-1080 may have therapeutic potential for the treatment of vascular diseases such as restenosis and atherosclerosis."
3.	Vascular Diseases (Vascular Disease) 10/01/2002 - "These results suggest that SK-1080 may have therapeutic potential for the treatment of vascular diseases such as restenosis and atherosclerosis."
4.	Tachycardia (Tachyarrhythmias) 03/01/1999 - "On repeated dosing for 21 days in SHRs, SK-1080 significantly reduced blood pressure without inducing tachycardia and tolerance throughout the dosing period. "
5.	Infarction (Infarctions) 12/01/2010 - "The elevated uptake of (11)C-KR31173 in the infarct area was detectable by small-animal PET in vivo, and it was blocked completely by intravenous SK-1080. "