NPS R-467
calcimimetic compound; structure given in first source
Networked: 2
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Hyperparathyroidism
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| 2. | Nephrocalcinosis
05/01/2004
- " Effect of the calcimimetic NPS R-467 on furosemide-induced nephrocalcinosis in the young rat." 05/01/2004
- " To determine whether NPS R-467 could, like parathyroidectomy, prevent furosemide-induced nephrocalcinosis, we studied 35 6-week-old male Sprague-Dawley rats, divided into five groups. " 05/01/2004
- " The calcimimetic agent NPS R-467 prevents the development of hyperparathyroidism and attenuates nephrocalcinosis in the furosemide-treated young rat." 05/01/2004
- " Treatment with NPS R-467 ameliorated the furosemide-induced increase in kidney calcium content (673 +/- 312 microg/g, 361 +/- 188 microg/g, and 563 +/- 291 microg/g) and nephrocalcinosis scoring (2.2 +/- 1.2, 0.7 +/- 0.8, and 1.0 +/- 1.2) in groups C, D, and E, respectively. "
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| 3. | Secondary Hyperparathyroidism
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